The technique of limbal autograft transplantation is presented which has been used in 25 cases of uniocular chemical and thermal burns. With up to 4 years follow-up, these cases have consistently demonstrated: (1) improved visual acuity; (2) rapid surface healing; (3) stable epithelial adhesion without recurrent erosion or persistent epithelial defect; (4) consistent regression of corneal neovascularization; (5) restoration of a smooth and optically improved ocular surface; and (6) probably increased success for subsequent keratoplasty.