Reactivity between monoclonal anti-HLA-B27 antibodies and bacterial components: is there a consensus of findings?

M N Ren; J J Zhang; A Nakayama; D T Yu

doi:10.1007/BF00271884

Reactivity between monoclonal anti-HLA-B27 antibodies and bacterial components: is there a consensus of findings?

Rheumatol Int. 1989;9(3-5):219-21. doi: 10.1007/BF00271884.

Authors

M N Ren¹, J J Zhang, A Nakayama, D T Yu

Affiliation

¹ Department of Medicine, University of California Center for Health Sciences, Los Angeles 90024.

PMID: 2692129
DOI: 10.1007/BF00271884

Abstract

Studies addressing the molecular aspects of the postulated cross-reactivity between the HLA-B27 antigens and the bacteria known to precipitate arthritis (e.g., Shigella, Salmonella, Yersinia and Campylobacter) are reviewed. In conclusion, the necessity for further research into the pathogenesis of arthritis is stressed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Amino Acid Sequence
Antibodies, Monoclonal / immunology*
Arthritis, Infectious / immunology
Bacterial Outer Membrane Proteins / immunology*
Cross Reactions / immunology*
Enterobacteriaceae / immunology
HLA-B27 Antigen / immunology*
Humans
Molecular Sequence Data

Substances

Antibodies, Monoclonal
Bacterial Outer Membrane Proteins
HLA-B27 Antigen

Grants and funding

AR 36 834/AR/NIAMS NIH HHS/United States