The influence of systemic drugs on tear constituents

Ophthalmology. 1979 Jan;86(1):115-25. doi: 10.1016/s0161-6420(79)35541-5.

Abstract

Tears of patients and laboratory animals on systemic medications have been analyzed for the presence and influence of these agents on tear constituents. Antibiotic penetration into tears, drugs stimulating or retarding lacrimation, and effects on tear electrolytes, lysozyme, and immunoglobulins are reviewed from the literature. Important applications to clinical practice such as contact lens wear, general anesthesia, eye infections, and epiphora or dry eye symptoms are discussed.

MeSH terms

  • Anesthetics / pharmacology
  • Anti-Bacterial Agents / pharmacology
  • Antihypertensive Agents / pharmacology
  • Contact Lenses
  • Humans
  • Muramidase / analysis
  • Parasympatholytics / pharmacology
  • Parasympathomimetics / pharmacology
  • Pharmaceutical Preparations / analysis
  • Pharmacology*
  • Sympathomimetics / pharmacology
  • Tears / analysis
  • Tears / drug effects*
  • Tears / physiology

Substances

  • Anesthetics
  • Anti-Bacterial Agents
  • Antihypertensive Agents
  • Parasympatholytics
  • Parasympathomimetics
  • Pharmaceutical Preparations
  • Sympathomimetics
  • Muramidase