Information on the fate of the fellow eye in patients who have suffered loss of central vision in the first eye due to exudative senile maculopathy suggests that there is a high incidence of later loss of vision in the second eye due to the same disease process. It has been speculated that prophylactic photocoagulation of the macula in the fellow eye might have a protective effect. This is a preliminary report of a series of patients in which argon laser photocoagulation of the second eye has been performed.