Subretinal neovascularization in senile macular degeneration

Am J Ophthalmol. 1984 Feb;97(2):143-7. doi: 10.1016/s0002-9394(14)76083-0.

Abstract

When fluorescein angiograms from 563 patients with senile macular degeneration examined at a large community hospital during a 9.5-year period were retrospectively reviewed, 200 patients were found to have a dry atrophic type of senile macular degeneration, consisting of drusen and retinal pigment epithelial changes. Of the 363 patients with exudative senile macular degeneration, 244 had subretinal neovascular membranes. Seventy-eight membranes were less than 1 disk diameter in size. Most of the large (157 of 224) and small (44 of 78) membranes showed a predilection for the fovea. Only 13 large and six small neovascular membranes were 200 microns or more from the center of the foveal avascular zone.

MeSH terms

  • Fluorescein Angiography
  • Humans
  • Light Coagulation
  • Macular Degeneration / complications*
  • Macular Degeneration / physiopathology
  • Macular Degeneration / therapy
  • Neovascularization, Pathologic / etiology*
  • Neovascularization, Pathologic / pathology
  • Retina / blood supply*
  • Retrospective Studies
  • Visual Acuity