Schirmer's test. A closer look

Arch Ophthalmol. 1983 Sep;101(9):1383-6. doi: 10.1001/archopht.1983.01040020385009.

Abstract

In 50 normal subjects, results of kinetics studies of Schirmer's test demonstrated nonlinear wetting with an initial rapid phase of wetting followed by a progressive reduction in rate. This initial rapid phase of wetting indicated a reflex secretion of tears. In the majority of subjects, topical anesthesia with 0.5% proparacaine hydrochloride dampened the initial reflex secretion but could not completely suppress it. The data indicated that Schirmer's test with anesthesia was not capable of measuring a basic tear secretion independent of reflex components.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anesthetics, Local / pharmacology*
  • Humans
  • Lacrimal Apparatus / drug effects
  • Lacrimal Apparatus / metabolism*
  • Middle Aged
  • Propoxycaine / pharmacology
  • Reflex
  • Tears / metabolism*

Substances

  • Anesthetics, Local
  • proxymetacaine
  • Propoxycaine