Posterior sub-Tenon injections of repository corticosteroids in uveitis patients with cystoid macular edema

Jpn J Ophthalmol. 1995;39(1):71-6.

Abstract

Repository corticosteroid was injected into the posterior sub-Tenon space in 29 cases (39 eyes) of cystoid macular edema (CME) secondary to uveitis. There were 12 cases of Behçet's disease, 7 cases of sarcoidosis, one case of tuberculous uveitis, and 9 cases of etiology unknown uveitis. In some of the patients injections were repeated 2 to 7 times at intervals of more than 2 weeks. Twenty-two of the 39 treated eyes (56.4%) showed visual improvement in at least two lines of visual acuity. Fifteen of the 22 eyes had maintained improved visual acuity over 6 months. Eleven eyes showed no improvement in vision. Most of them already had poor visual acuity (0.2 or less) before the injections. Complications of the treatment included cataract in 6 eyes, glaucoma in one, and blepharoptosis in one. Injection of repository corticosteroids into the posterior sub-Tenon space is of value in the treatment of CME secondary to uveitis. However, we have to beware of the complications of treatment.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Fascia / drug effects
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Injections
  • Macular Edema / drug therapy*
  • Macular Edema / etiology
  • Male
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / adverse effects
  • Methylprednisolone / therapeutic use*
  • Middle Aged
  • Orbit / drug effects
  • Prognosis
  • Suspensions
  • Triamcinolone / administration & dosage
  • Triamcinolone / adverse effects
  • Triamcinolone / therapeutic use*
  • Uveitis / complications*
  • Visual Acuity

Substances

  • Suspensions
  • Triamcinolone
  • Methylprednisolone