The association between angle-closure glaucoma and pseudoexfoliation is controversial. We retrospectively studied the angle configurations of 54 patients with pseudoexfoliation and found gonioscopically occludable angles in five cases (9.3%). We also analyzed the data from several large studies of pseudoexfoliation patients and found an increased prevalence of acute angle-closure glaucoma in this group. These data suggest that pseudoexfoliation patients may represent a high-risk population for the development of angle-closure glaucoma.