Evaluation of the Kodak Surecell Chlamydia test for the laboratory diagnosis of adult inclusion conjunctivitis

Ophthalmology. 1995 Jul;102(7):1035-7. doi: 10.1016/s0161-6420(95)30915-3.

Abstract

Purpose: The Kodak Surecell Chlamydia test, a rapid enzyme immunoassay, has been reported to be highly sensitive (93%) and specific (96%) for detecting chlamydial lipopolysaccharide antigen in conjunctival specimens from infants, but has not been evaluated previously in adult conjunctival specimens. This study was designed to determine the efficacy of the Kodak Surecell Chlamydia test for the laboratory diagnosis of adult inclusion conjunctivitis.

Methods: Twenty Chlamydia culture-positive conjunctival specimens from adults (true-positives) and 20 true-negative specimens were tested with the Kodak Surecell Chlamydia test.

Results: The Kodak Surecell Chlamydia test was 40% (8/20) sensitive, 100% (20/20) specific, and 70% (28/40) efficient.

Conclusions: This study indicates that the Kodak Surecell Chlamydia test, though highly specific, is less sensitive in its ability to diagnose chlamydial conjunctivitis in adults than has been reported previously in infants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antigens, Bacterial / analysis*
  • Chlamydia trachomatis / immunology*
  • Chlamydia trachomatis / isolation & purification
  • Conjunctiva / microbiology
  • Conjunctivitis, Inclusion / diagnosis*
  • Conjunctivitis, Inclusion / microbiology
  • False Positive Reactions
  • Female
  • Humans
  • Immunoenzyme Techniques*
  • Lipopolysaccharides / analysis*
  • Male
  • Predictive Value of Tests
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity

Substances

  • Antigens, Bacterial
  • Lipopolysaccharides
  • Reagent Kits, Diagnostic