Abstract
This report describes an unusual reaction to injected subconjunctival corticosteroid. The authors examined a patient with large areas of conjunctival necrosis at the site of a previous subconjunctival corticosteroid injection. A Gram's strain and culture of the affected conjunctival area and the bottled corticosteroid suspension were negative. Necrosis of the conjunctiva is a heretofore unreported adverse reaction to a subconjunctival corticosteroid injection. These lesions probably represent a localized toxic reaction rather than a sequela of infection.
MeSH terms
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Aged
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Aged, 80 and over
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / adverse effects*
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Anti-Inflammatory Agents / therapeutic use
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Conjunctiva / drug effects*
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Conjunctiva / pathology
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Conjunctival Diseases / chemically induced*
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Conjunctival Diseases / pathology
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Female
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Fluorescein Angiography
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Follow-Up Studies
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Fundus Oculi
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Humans
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Injections
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Macular Edema / drug therapy
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Methylprednisolone / administration & dosage
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Methylprednisolone / adverse effects
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Methylprednisolone / analogs & derivatives*
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Methylprednisolone / therapeutic use
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Methylprednisolone Acetate
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Necrosis
Substances
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Anti-Inflammatory Agents
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Methylprednisolone Acetate
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Methylprednisolone