To illuminate the disease progression in retinopathy centralis serosa, 50 patients were enrolled in a basic study. Evaluated data included medical and sociodemographic data as well as data regarding the patient's coping with everyday conflicts and the disease. Hence, the German multidimensional coping inventory (SVF, Janke, Erdmann u. Boucsein 1985), measuring the trait aspects of coping with everyday troubles, as well as the German coping questionnaire (EFK, Franke 1997), dealing with coping with retinopathy, were applied. We described three different clusters of patients according to active and passive coping strategies. These three clusters also differed in terms of coping with the disease as well as in ophthalmological parameters. To illuminate the individual situation of the members of the clusters, we discuss the specific situation of three patients.