Abstract
We describe a case of focal cytomegalovirus iritis in a patient with acquired immunodeficiency syndrome (AIDS) who had CMV retinitis. The autopsy showed histologic evidence of focal iritis in the left eye. This iritis was characterized by infiltration of acute inflammatory cells mixed with cytomegalic cells, which was confirmed by CMV-specific immunohistochemical staining. The case suggested that cytomegalovirus could be a direct causative agent of infectious iritis in AIDS patients.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy
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AIDS-Related Opportunistic Infections / virology
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Adult
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Antibodies, Viral / analysis
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Antigens, Viral / immunology
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Antiviral Agents / therapeutic use
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Cidofovir
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Cytomegalovirus / immunology
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Cytomegalovirus / isolation & purification
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Cytomegalovirus Infections / drug therapy
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Cytomegalovirus Infections / pathology
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Cytomegalovirus Infections / virology*
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Cytomegalovirus Retinitis / drug therapy
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Cytomegalovirus Retinitis / virology
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Cytosine / analogs & derivatives
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Cytosine / therapeutic use
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Fatal Outcome
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Humans
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Immunohistochemistry
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Iris / pathology
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Iris / virology*
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Iritis / drug therapy
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Iritis / pathology
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Iritis / virology*
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Male
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Organophosphonates*
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Organophosphorus Compounds / therapeutic use
Substances
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Antibodies, Viral
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Antigens, Viral
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Antiviral Agents
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Organophosphonates
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Organophosphorus Compounds
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Cytosine
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Cidofovir