[HTML][HTML] Nature, nurture, or chance: stochastic gene expression and its consequences
A Raj, A Van Oudenaarden - Cell, 2008 - cell.com
Gene expression is a fundamentally stochastic process, with randomness in transcription
and translation leading to cell-to-cell variations in mRNA and protein levels. This variation …
and translation leading to cell-to-cell variations in mRNA and protein levels. This variation …
Barriers to the adoption of industry 4.0 technologies in the manufacturing sector: An inter-country comparative perspective
This paper examines barriers to the implementation of Industry 4.0 technologies in the
manufacturing sector in the context of both developed and developing economies. A …
manufacturing sector in the context of both developed and developing economies. A …
Gender inequality and restrictive gender norms: framing the challenges to health
Gender is not accurately captured by the traditional male and female dichotomy of sex.
Instead, it is a complex social system that structures the life experience of all human beings …
Instead, it is a complex social system that structures the life experience of all human beings …
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
We recently showed that the mammalian genome encodes> 1,000 large intergenic
noncoding (linc) RNAs that are clearly conserved across mammals and, thus, functional …
noncoding (linc) RNAs that are clearly conserved across mammals and, thus, functional …
Imaging individual mRNA molecules using multiple singly labeled probes
We describe a method for imaging individual mRNA molecules in fixed cells by probing
each mRNA species with 48 or more short, singly labeled oligonucleotide probes. This …
each mRNA species with 48 or more short, singly labeled oligonucleotide probes. This …
[HTML][HTML] Bayesian inference for psychology. Part II: Example applications with JASP
…, B Boutin, F Meerhoff, P Knight, A Raj… - Psychonomic bulletin & …, 2018 - Springer
Bayesian hypothesis testing presents an attractive alternative to p value hypothesis testing.
Part I of this series outlined several advantages of Bayesian hypothesis testing, including the …
Part I of this series outlined several advantages of Bayesian hypothesis testing, including the …
Dating violence against adolescent girls and associated substance use, unhealthy weight control, sexual risk behavior, pregnancy, and suicidality
ContextIntimate partner violence against women is a major public health concern. Research
among adults has shown that younger age is a consistent risk factor for experiencing and …
among adults has shown that younger age is a consistent risk factor for experiencing and …
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
Therapies that target signalling molecules that are mutated in cancers can often have
substantial short-term effects, but the emergence of resistant cancer cells is a major barrier …
substantial short-term effects, but the emergence of resistant cancer cells is a major barrier …
Control of somatic tissue differentiation by the long non-coding RNA TINCR
Several of the thousands of human long non-coding RNAs (lncRNAs) have been
functionally characterized,,,; however, potential roles for lncRNAs in somatic tissue …
functionally characterized,,,; however, potential roles for lncRNAs in somatic tissue …
[HTML][HTML] Stochastic mRNA synthesis in mammalian cells
A Raj, CS Peskin, D Tranchina, DY Vargas… - PLoS biology, 2006 - journals.plos.org
Individual cells in genetically homogeneous populations have been found to express
different numbers of molecules of specific proteins. We investigated the origins of these …
different numbers of molecules of specific proteins. We investigated the origins of these …