Importance Systematic reviews of diagnostic test accuracy synthesize data from primary
diagnostic studies that have evaluated the accuracy of 1 or more index tests against a …

Background: Coronavirus disease 2019 (COVID-19)–related critical illness and acute illness
are associated with a risk of venous thromboembolism (VTE). Objective: These evidence …

Soil provides ecosystem services, supports human health and habitation, stores carbon and
regulates emissions of greenhouse gases. Unprecedented pressures on soil from …

Macrophages orchestrate innate immunity by phagocytosing pathogens and coordinating
inflammatory responses. Effective defence requires the host to discriminate between …

PROSTAGLANDINSand glucocorticoids are potent mediators of inflammation. Non-steroidal
anti-inflammatory drugs (NSAIDs) exert their effects by inhibition of prostaglandin …

This classic volume compiles and describes interdisciplinary research on the formal nature
of human knowledge about the world. Three key dimensions that characterize mental …

The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …

Importance Coronavirus disease 2019 (COVID-19) may lead to serious illness as a result of
an excessive immune response. Fluvoxamine may prevent clinical deterioration by …

Recent studies indicate a link between carbohydrate intake and the functional state of the
sympathetic nervous system. Fasting or carbohydrate restriction decreases sympathetic …

Background Depression is a major individual and public-health burden throughout the world
and is managed mainly in primary care. The most effective strategy to reduce this burden …