Validation of automated screening for referable diabetic retinopathy with the IDx‐DR device in the Hoorn Diabetes Care System
AA Van Der Heijden, MD Abramoff… - Acta …, 2018 - Wiley Online Library
Purpose To increase the efficiency of retinal image grading, algorithms for automated
grading have been developed, such as the IDx‐DR 2.0 device. We aimed to determine the …
grading have been developed, such as the IDx‐DR 2.0 device. We aimed to determine the …
[HTML][HTML] Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting
AA van der Heijden, G Nijpels, F Badloe, HL Lovejoy… - Diabetologia, 2020 - Springer
Aims/hypothesis The aims of this study were to identify all published prognostic models
predicting retinopathy risk applicable to people with type 2 diabetes, to assess their quality …
predicting retinopathy risk applicable to people with type 2 diabetes, to assess their quality …
The association between social jetlag, the metabolic syndrome, and type 2 diabetes mellitus in the general population: the new Hoorn study
ADM Koopman, SP Rauh, E van 't Riet… - Journal of biological …, 2017 - journals.sagepub.com
Only a few studies have investigated the metabolic consequences of social jetlag. Therefore,
we examined the association of social jetlag with the metabolic syndrome and type 2 …
we examined the association of social jetlag with the metabolic syndrome and type 2 …
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
K Zhou, SW Yee, EL Seiser, N Van Leeuwen… - Nature …, 2016 - nature.com
Metformin is the first-line antidiabetic drug with over 100 million users worldwide, yet its
mechanism of action remains unclear. Here the Metformin Genetics (MetGen) Consortium …
mechanism of action remains unclear. Here the Metformin Genetics (MetGen) Consortium …
[HTML][HTML] Identification of biomarkers for glycaemic deterioration in type 2 diabetes
RC Slieker, LA Donnelly, E Akalestou… - Nature …, 2023 - nature.com
We identify biomarkers for disease progression in three type 2 diabetes cohorts
encompassing 2,973 individuals across three molecular classes, metabolites, lipids and …
encompassing 2,973 individuals across three molecular classes, metabolites, lipids and …
Variants in pharmacokinetic transporters and glycemic response to metformin: a Metgen meta‐analysis
Therapeutic response to metformin, a first‐line drug for type 2 diabetes (T2D), is highly
variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies …
variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies …
[HTML][HTML] Prognostic models for predicting the risk of foot ulcer or amputation in people with type 2 diabetes: a systematic review and external validation study
JWJ Beulens, JS Yauw, PJM Elders, T Feenstra… - Diabetologia, 2021 - Springer
Aims/hypothesis Approximately 25% of people with type 2 diabetes experience a foot ulcer
and their risk of amputation is 10–20 times higher than that of people without type 2 …
and their risk of amputation is 10–20 times higher than that of people without type 2 …
Diagnostic accuracy of a device for the automated detection of diabetic retinopathy in a primary care setting
FD Verbraak, MD Abramoff, GCF Bausch… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE To determine the diagnostic accuracy in a real-world primary care setting of a
deep learning–enhanced device for automated detection of diabetic retinopathy (DR) …
deep learning–enhanced device for automated detection of diabetic retinopathy (DR) …
[HTML][HTML] Intimal and medial calcification in relation to cardiovascular risk factors
SR Zwakenberg, PA de Jong, EJ Hendriks… - PLoS …, 2020 - journals.plos.org
Purpose To assess specific risk factors and biomarkers associated with intimal arterial
calcification (IAC) and medial arterial calcification (MAC). Methods We conducted a cross …
calcification (IAC) and medial arterial calcification (MAC). Methods We conducted a cross …
The effect of a screening and treatment program for the prevention of fractures in older women: a randomized pragmatic trial
T Merlijn, KMA Swart, NM van Schoor… - Journal of Bone and …, 2019 - academic.oup.com
Population screening for fracture risk may reduce the fracture incidence. In this randomized
pragmatic trial, the SALT Osteoporosis Study (SOS), we studied whether screening for …
pragmatic trial, the SALT Osteoporosis Study (SOS), we studied whether screening for …