Rising prevalence of diabetes worldwide has necessitated the implementation of population-
based diabetic retinopathy (DR) screening programs that can perform retinal imaging and …

Inherited retinal diseases (IRDs) are a heterogenous group of orphan eye diseases that
typically result from monogenic mutations and are considered attractive targets for gene …

Polypoidal choroidal vasculopathy (PCV) is a subtype of neovascular AMD (nAMD) that
accounts for a significant proportion of nAMD cases worldwide, and particularly in Asia …

Betanodaviruses are small positive-sense bipartite RNA viruses that infect a wide variety of
fish species and are notorious for causing lethal outbreaks in juvenile fish hatcheries …

Purpose Optical coherence tomography angiography (OCT-A) potentially allows for rapid
and non-invasive quantification of retinal capillary plexus density in various disease states …

Betanodavirus B2 belongs to a group of functionally related proteins from the sense-strand
RNA virus family Nodaviridae that suppress cellular RNA interference. The B2 proteins of …

Attachment of ubiquitin to proteins represents a central mechanism for the regulation of
protein metabolism and function. In the NF-kappaB pathway, binding of NEMO to …

Objective To assess the economic impact of inherited retinal disease (IRD) among
Singaporeans. Methods IRD prevalence was calculated using population-based data …

We have characterized a white spot syndrome virus (WSSV) RING-H2-type protein,
WSSV222, which is involved in ubiquitination. WSSV222 exhibits RING-H2-dependent E3 …

Purpose To describe the 12-month outcomes of treatment-naïve eyes with choroidal
neovascularization (CNV) resulting from age-related macular degeneration (AMD) and …