Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal
melanomas. These cancers represent 5% of all melanoma diagnoses in the United States …

Breast carcinoma continues to account for the majority of metastatic lesions of the orbit and
ocular adnexa. Although the overall prognosis for patients with such lesions remains poor …

Sebaceous carcinoma usually occurs in adults older than 60 years, on the eyelid, head and
neck, and trunk. In this Review, we present clinical care recommendations for sebaceous …

Purpose: ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of
paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without …

Comprehensive multiplatform analysis of 80 uveal melanomas (UM) identifies four
molecularly distinct, clinically relevant subtypes: two associated with poor-prognosis …

PURPOSE: To evaluate the safety and efficacy of weekly docetaxel plus trastuzumab in
women with HER-2–overexpressing metastatic breast cancer. Efficacy was correlated with …

Purpose: Ocular trauma is a leading cause of blindness in the United States. This study was
undertaken to identify clinical and histopathologic factors that predict ocular survival and …

Erdheim-Chester disease is a rare non-Langerhans histiocytosis with multisystem
involvement. To date, there is no standard treatment for this disorder, and more than half of …

Abstract Purpose: Activating Q209L/P mutations in GNAQ or GNA11 (GNAQ/11) are present
in approximately 80% of uveal melanomas. Mutant GNAQ/11 are not currently …

OBJECTIVE: To report a newly recognized side effect of a commonly used antineoplastic
agent, docetaxel, in three patients with metastatic breast cancer. DESIGN: Observational …