Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration

A Wenzel, C Grimm, M Samardzija, CE Remé - Progress in retinal and eye …, 2005 - Elsevier
Human retinal dystrophies and degenerations and light-induced retinal degenerations in
animal models are sharing an important feature: visual cell death by apoptosis. Studying …

Apoptotic cell death in retinal degenerations

CE Remé, C Grimm, F Hafezi, A Marti… - Progress in retinal and eye …, 1998 - Elsevier
Apoptosis is a regulated mode of single cell death that involves gene expression in many
instances and occurs under physiological and pathological conditions in a large variety of …

[HTML][HTML] European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer

…, M Genuardi, L Gladieff, R Glasspool, C Grimm… - Annals of …, 2022 - Elsevier
Background Homologous recombination repair (HRR) enables fault-free repair of double-
stranded DNA breaks. HRR deficiency is predicted to occur in around half of high-grade …

The role of competitive action in market share erosion and industry dethronement: A study of industry leaders and challengers

WJ Ferrier, KG Smith, CM Grimm - Academy of management …, 1999 - journals.aom.org
Market share erosion and dethronement of market leaders are examined through the lens of
“Austrian” economics. Our results suggest that leaders are more likely to experience market …

Environmental purchasing and firm performance: an empirical investigation

CR Carter, R Kale, CM Grimm - Transportation Research Part E: Logistics …, 2000 - Elsevier
Much debate has occurred in the extant literature as to whether socially responsible actions
undertaken by firms result in improved financial performance. One key dimension of social …

Organizational information processing, competitive responses, and performance in the US domestic airline industry

KG Smith, CM Grimm, MJ Gannon… - … of Management journal, 1991 - journals.aom.org
This study investigates how firms build competitive advantage by focusing on the actions
and responses of rivals in the US domestic airline industry. We identified four attributes of …

HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

C Grimm, A Wenzel, M Groszer, H Mayser… - Nature medicine, 2002 - nature.com
Erythropoietin (Epo) is upregulated by hypoxia and provides protection against apoptosis of
erythroid progenitors in bone marrow and brain neurons. Here we show in the adult mouse …

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

…, MW Tidwell, WE Bauta, N Klugbauer, C Grimm… - Science, 2015 - science.org
Ebola virus causes sporadic outbreaks of lethal hemorrhagic fever in humans, but there is
no currently approved therapy. Cells take up Ebola virus by macropinocytosis, followed by …

Action characteristics as predictors of competitive responses

MJ Chen, KG Smith, CM Grimm - Management science, 1992 - pubsonline.informs.org
A central question in competitive dynamics is whether a competitive response can be
predicted. This study links various characteristics of actions with the total number and the …

The impact of market actions on firm reputation

DK Basdeo, KG Smith, CM Grimm… - Strategic …, 2006 - Wiley Online Library
Drawing on signaling theory, we hypothesize that a firm's reputation is shaped by its own
market actions and the actions of its industry rivals. We view market actions as signals that …