[HTML][HTML] Non-syndromic retinitis pigmentosa

SK Verbakel, RAC van Huet, CJF Boon… - Progress in retinal and …, 2018 - Elsevier
Retinitis pigmentosa (RP) encompasses a group of inherited retinal dystrophies
characterized by the primary degeneration of rod and cone photoreceptors. RP is a leading …

[HTML][HTML] The complications of myopia: a review and meta-analysis

AEG Haarman, CA Enthoven… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: To determine the risk between degree of myopia and myopic macular
degeneration (MMD), retinal detachment (RD), cataract, open angle glaucoma (OAG), and …

Epidemiology of age-related maculopathy: a review

R van Leeuwen, CCW Klaver, JR Vingerling… - European journal of …, 2003 - Springer
Age-related maculopathy (ARM) is a degenerative disease of the retina and the leading
cause of incurable blindness and visual impairment in industrialized countries. By definition …

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

GS Hageman, DH Anderson… - Proceedings of the …, 2005 - National Acad Sciences
Age-related macular degeneration (AMD) is the most frequent cause of irreversible
blindness in the elderly in developed countries. Our previous studies implicated activation of …

Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study

CCW Klaver, RCW Wolfs, JR Vingerling… - Archives of …, 1998 - jamanetwork.com
Objective To study the prevalence and causes of blindness and visual impairment in various
age categories of a large population-based study. Methods For the study, 6775 subjects …

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

LG Fritsche, W Igl, JNC Bailey, F Grassmann… - Nature …, 2016 - nature.com
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …

Risk factors for age-related macular degeneration: pooled findings from three continents

W Smith, J Assink, R Klein, P Mitchell, CCW Klaver… - Ophthalmology, 2001 - Elsevier
OBJECTIVE: To assess the prevalence and potential risk factors for late age-related macular
degeneration (AMD) in three racially similar populations from North America, Europe, and …

Genetic risk of primary open-angle glaucoma: population-based familial aggregation study

RCW Wolfs, CCW Klaver, RS Ramrattan… - Archives of …, 1998 - jamanetwork.com
Objectives To study familial aggregation of primary open-angle glaucoma in a general
population and to determine the absolute and relative risks for first-degree relatives …

Distribution of central corneal thickness and its association with intraocular pressure: The Rotterdam Study

RCW Wolfs, CCW Klaver, JR Vingerling… - American journal of …, 1997 - Elsevier
Purpose To perform a cross-sectional study on the distribution of central corneal thickness
and its association with intraocular pressure in an elderly population. Methods We …

[HTML][HTML] The Generation R Study: design and cohort update 2017

MN Kooijman, CJ Kruithof, CM van Duijn… - European journal of …, 2016 - Springer
Abstract The Generation R Study is a population-based prospective cohort study from fetal
life until adulthood. The study is designed to identify early environmental and genetic causes …