Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …

The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host
disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable …

The purpose of the present study was to quantify and compare corneal hem-and
lymphangiogenesis between alkali burn and suture-induced corneal neovascularization …

Purpose.: To evaluate the safety/efficacy of topical infliximab, an anti-TNF-α monoclonal
antibody, in a mouse model of ocular surface scarring. Methods.: Twenty alkali burn mice …

Purpose.: To test whether a corneal injury can stimulate inflammation in the trigeminal
ganglion (TG), a structure located in the brain. Methods.: At 4 and 8 days after alkali burn …

Purpose.: To determine whether the inhibition of Substance P (SP) activity can reduce
corneal neovascularization (CNV) by means of local administration of high-affinity …

In vivo apoptosis of human mesenchymal stromal cells (MSCs) plays a critical role in
delivering immunomodulation. Yet, caspase activity not only mediates the dying process but …

Introduction: The aim of therapy in Crohn's disease (CD) is induction and maintenance of
remission, promotion of mucosal healing and restoration of quality of life. Even the best …

Purpose To define proangiogenic angiopoietin 2 (ANG2) expression and role (s) in human
and mouse vascularised corneas. Further, to evaluate the effect of ANG2 inhibition on …

Chimeric Antigen Receptor (CAR)-T cells have proven highly successful in the treatment of
some haemopoietic neoplasms. However, in several cases the treatment fails and disease …