Abstract BACKGROUND: In September 2007, the Food and Drug Administration (FDA)
strengthened label warnings for intravenous (IV) haloperidol regarding QT prolongation …

Purpose The accuracy, efficiency, and efficacy of four commonly recommended medication
safety assessment methodologies were systematically reviewed. Methods Medical literature …

Sun protection is a major concern for outdoor workers as they are particularly exposed to
solar ultraviolet radiation and therefore at increased risk of developing some forms of skin …

ContextRecent animal studies have suggested that 3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase inhibitors (statins) increase bone formation, volume, and density. It is …

The United Kingdom General Practice Research Database (GPRD) is an office‐based,
computer‐generated, medical resource designed from its inception to be used for …

OBJECTIVE To evaluate whether use of oral hypoglycemic agents is associated with an
altered breast cancer risk in women. RESEARCH DESIGN AND METHODS Using the UK …

OBJECTIVE—Lactic acidosis has been associated with use of metformin. Hypoglycemia is a
major concern using sulfonylureas. The aim of this study was to compare the risk of lactic …

Background There is growing interest in the role of infections in the aetiology of acute
myocardial infarction (AMI). We undertook a large, population-based study to explore the …

ContextAnimal studies suggest that the β-blocker propranolol increases bone formation, but
data on whether use of β-blockers (with or without concomitant use of thiazide diuretics) is …

Background Thiazolidinediones may adversely affect the skeleton owing to decreased bone
formation and accelerated bone loss. Methods This study examines the association between …