Primary open-angle glaucoma

RN Weinreb, CKS Leung, JG Crowston… - Nature reviews Disease …, 2016 - nature.com
Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …

Comparison of macular and peripapillary measurements for the detection of glaucoma: an optical coherence tomography study

CKS Leung, WM Chan, WH Yung, ACK Ng, J Woo… - Ophthalmology, 2005 - Elsevier
OBJECTIVE: To evaluate macular nerve fiber layer (NFL) thickness in glaucomatous
damage by optical coherence tomography (OCT) and to compare its discriminating power …

Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a prospective analysis of age-related loss

CKS Leung, M Yu, RN Weinreb, C Ye, S Liu, G Lai… - Ophthalmology, 2012 - Elsevier
OBJECTIVE: To investigate age-related changes of the retinal nerve fiber layer (RNFL)
imaged by a spectral-domain optical coherence tomography (OCT). DESIGN: Prospective …

Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: analysis of the retinal nerve fiber layer map for glaucoma detection

CKS Leung, S Lam, RN Weinreb, S Liu, C Ye, L Liu… - Ophthalmology, 2010 - Elsevier
OBJECTIVE: To evaluate the diagnostic performance of the retinal nerve fiber layer (RNFL)
thickness deviation map imaged by a spectral-domain optical coherence tomography (OCT; …

[HTML][HTML] Minimally invasive glaucoma surgery in primary angle-closure glaucoma

Y Song, H Zhang, Y Zhang, G Tang… - The Asia-Pacific …, 2022 - journals.lww.com
Primary angle-closure glaucoma (PACG) is responsible for half of the glaucoma-related
blindness worldwide. Cataract surgery with or without trabeculectomy has been considered …

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

Y Chen, Y Lin, EN Vithana, L Jia, X Zuo, TY Wong… - Nature …, 2014 - nature.com
We performed a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …

Impact of age-related change of retinal nerve fiber layer and macular thicknesses on evaluation of glaucoma progression

CKS Leung, C Ye, RN Weinreb, M Yu, G Lai, DS Lam - Ophthalmology, 2013 - Elsevier
Objective To investigate the impact of age-related change of macular and circumpapillary
retinal nerve fiber layer (RNFL) measurements on evaluation of glaucoma progression …

Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: pattern of RNFL defects in glaucoma

CKS Leung, N Choi, RN Weinreb, S Liu, C Ye, L Liu… - Ophthalmology, 2010 - Elsevier
OBJECTIVE: To characterize the distribution pattern, angular width, and area of retinal nerve
fiber layer (RNFL) defects in glaucoma using spectral-domain optical coherence …

Agreement among 3 methods to measure corneal thickness: ultrasound pachymetry, Orbscan II, and Visante anterior segment optical coherence tomography

EYM Li, S Mohamed, CKS Leung, SK Rao, ACK Cheng… - Ophthalmology, 2007 - Elsevier
PURPOSE: To assess the agreement of central and paracentral corneal thickness
measurements between ultrasound pachymetry (USP), Orbscan II, and Visante anterior …

A common variant near TGFBR3 is associated with primary open angle glaucoma

Z Li, RR Allingham, M Nakano, L Jia… - Human molecular …, 2015 - academic.oup.com
Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex
disease with a significant genetic contribution. We performed Exome Array (Illumina) …