The heart is a major target organ for thyroid hormone action, and marked changes occur in
cardiac function in patients with hypo-or hyperthyroidism. T3-induced changes in cardiac …

Subclinical hypothyroidism (SH) is common, especially among elderly women. There is no
clear evidence to date that SH causes clinical heart disease. However, mild thyroid gland …

Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

Methods European Group on GO (EUGOGO) represents a multidisciplinary consortium of
clinicians from the European centers, who share a commitment to improving the …

Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease (GD).
Choice of treatment should be based on the assessment of clinical activity and severity of …

Background Thyroid-associated ophthalmopathy, a condition commonly associated with
Graves' disease, remains inadequately treated. Current medical therapies, which primarily …

Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease, though
severe forms are rare. Management of GO is often suboptimal, largely because available …

Graves' orbitopathy (GO) constitutes a major clinical and therapeutic challenge (1, 2). GO is
an autoimmune disorder representing the commonest and most important extrathyroidal …

Background Oxygen free radicals and cytokines play a pathogenic role in Graves'
orbitopathy. Methods We carried out a randomized, double-blind, placebo-controlled trial to …

Context: Glucocorticoids are effective for severe Graves' orbitopathy (GO), which causes
substantial morbidity. The question at issue is how best to use them. Objective: The objective …