[HTML][HTML] Notch signaling: an emerging therapeutic target for cancer treatment
X Yuan, H Wu, H Xu, H Xiong, Q Chu, S Yu, GS Wu… - Cancer letters, 2015 - Elsevier
The Notch pathway is involved in cell proliferation, differentiation and survival. The Notch
signaling pathway is one of the most commonly activated signaling pathways in cancer …
signaling pathway is one of the most commonly activated signaling pathways in cancer …
The functional interactions between the MAPK and p53 signaling pathways
GS Wu - Cancer biology & therapy, 2004 - Taylor & Francis
The p53 tumor suppressor protein exerts its growth inhibitory activity by activating and
interacting with diverse signaling pathways. As a downstream target, p53 protein is …
interacting with diverse signaling pathways. As a downstream target, p53 protein is …
Neuroimmune interactions in peripheral organs
Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …
recent studies show that this crosstalk occurs more frequently than was previously …
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
GS Wu, TF Burns, ER McDonald 3rd… - Nature …, 1997 - pubmed.ncbi.nlm.nih.gov
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene KILLER/DR5 is a
DNA damage-inducible p53-regulated death receptor gene Nat Genet. 1997 Oct;17(2):141-3 …
DNA damage-inducible p53-regulated death receptor gene Nat Genet. 1997 Oct;17(2):141-3 …
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation
EL Carr, A Kelman, GS Wu, R Gopaul… - The Journal of …, 2010 - journals.aai.org
Activation of a naive T cell is a highly energetic event, which requires a substantial increase
in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and …
in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and …
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiPl
Much of the predisposition to hereditary breast and ovarian cancer has been attributed to
inherited defects in the BRCA1 tumour-suppressor gene,,. The nuclear protein BRCA1 has …
inherited defects in the BRCA1 tumour-suppressor gene,,. The nuclear protein BRCA1 has …
p53-dependent and -independent Regulation of the Death Receptor KILLER/DR5 Gene Expression in Response to Genotoxic Stress and Tumor Necrosis Factor α
MS Sheikh, TF Burns, Y Huang, GS Wu, S Amundson… - Cancer research, 1998 - AACR
The death receptor (DR) KILLER/DR5 gene has recently been identified as a doxorubicin-
regulated transcript that was also induced by exogenous wild-type p53 in p53-negative …
regulated transcript that was also induced by exogenous wild-type p53 in p53-negative …
Multiple maternal origins of chickens: out of the Asian jungles
YP Liu, GS Wu, YG Yao, YW Miao, G Luikart… - Molecular phylogenetics …, 2006 - Elsevier
Domestic chickens have long been important to human societies for food, religion,
entertainment, and decorative uses, yet the origins and phylogeography of chickens through …
entertainment, and decorative uses, yet the origins and phylogeography of chickens through …
Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects
JE Allen, G Krigsfeld, PA Mayes, L Patel… - Science translational …, 2013 - science.org
Recombinant tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is an
antitumor protein that is in clinical trials as a potential anticancer therapy but suffers from …
antitumor protein that is in clinical trials as a potential anticancer therapy but suffers from …
[HTML][HTML] Chicken domestication: an updated perspective based on mitochondrial genomes
YW Miao, MS Peng, GS Wu, YN Ouyang, ZY Yang… - Heredity, 2013 - nature.com
Domestic chickens (Gallus gallus domesticus) fulfill various roles ranging from food and
entertainment to religion and ornamentation. To survey its genetic diversity and trace the …
entertainment to religion and ornamentation. To survey its genetic diversity and trace the …