The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create
an evidence-based definition and a contemporary classification system for dry eye disease …

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and
progenitor cells. Clinically, it is associated with the selection and enrichment of …

The amniotic membrane is the innermost of the three layers forming the fetal membranes. It
was first used in 1910 in skin transplantation. Thereafter it has been used in surgical …

Purpose: To develop current treatment recommendations for dry eye disease from
consensus of expert advice. Methods: Of 25 preselected international specialists on dry eye …

Stem cells have certain unique characteristics, which include longevity, high capacity of self-
renewal with a long cell cycle time and a short S-phase duration, increased potential for …

Purpose To define and characterize a novel pre-Descemet's layer in the human cornea.
Design Clinical and experimental study. Participants We included 31 human donor …

AIMS To evaluate the efficacy of amniotic membrane transplantation (AMT) for ocular
surface reconstruction. METHODS 10 consecutive patients who underwent AMT were …

Corneal opacity is the 5th leading cause of blindness and visual impairment globally,
affecting~ 6 million of the world population. In addition, it is responsible for 1.5–2.0 million …

In 1910 Davis was the first to report the use of fetal membranes as surgical material in skin
transplantation. 1 Since then the use of amniotic membrane in surgery has been expanded …

Background/aims: There is substantial evidence that mammalian epithelial stem cells are
located within well defined niches. Although the corneoscleral limbus is acknowledged as …