[HTML][HTML] Vitamin D and ocular diseases: a systematic review

HN Chan, XJ Zhang, XT Ling, CHT Bui… - International journal of …, 2022 - mdpi.com
The contributory roles of vitamin D in ocular and visual health have long been discussed,
with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper …

Myopia incidence and lifestyle changes among school children during the COVID-19 pandemic: a population-based prospective study

X Zhang, SSL Cheung, HN Chan, Y Zhang… - British Journal of …, 2022 - bjo.bmj.com
Background The impacts of social restrictions for COVID-19 on children's vision and lifestyle
remain unknown. Aims To investigate myopia incidence, spherical equivalent refraction …

The association of choroidal thickening by atropine with treatment effects for myopia: two-year clinical trial of the low-concentration atropine for myopia progression …

JC Yam, Y Jiang, J Lee, S Li, Y Zhang, W Sun… - American Journal of …, 2022 - Elsevier
PURPOSE To evaluate longitudinal changes in subfoveal choroidal thickness (SFChT)
among children receiving atropine 0.05%, 0.025%, or 0.01% over 2 years and their …

[HTML][HTML] Total internal reflection-based single-vesicle in situ quantitative and stoichiometric analysis of tumor-derived exosomal microRNAs for diagnosis and treatment …

D He, H Wang, SL Ho, HN Chan, L Hai, X He… - Theranostics, 2019 - ncbi.nlm.nih.gov
Purpose: Exosomes (EXs) have been increasingly recognized as natural nanoscale
vehicles for microRNA (miRNA)-based cell-cell communication and an ideal source of …

[HTML][HTML] Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation

R You, YS Ho, CHL Hung, Y Liu, CX Huang… - Particle and fibre …, 2018 - Springer
Abstract Background Silica nanoparticles (SiO 2-NPs) are naturally enriched and broadly
utilized in the manufacturing industry. While previous studies have demonstrated toxicity in …

Molecular-recognition-based DNA nanodevices for enhancing the direct visualization and quantification of single vesicles of tumor exosomes in plasma microsamples

D He, SL Ho, HN Chan, H Wang, L Hai, X He… - Analytical …, 2019 - ACS Publications
Tumor exosomes (Exo) are presumed to expedite both the growth and metastasis of tumors
by actively participating in nearly all aspects of cancer development. Tumor-derived Exos …

[HTML][HTML] Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity

Y Li, D Xu, A Sun, SL Ho, CY Poon, HN Chan… - Chemical …, 2017 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent but still incurable neurodegenerative form of
dementia. Early diagnosis and intervention are crucial for delaying the onset and …

Multimodal Theranostic Cyanine-Conjugated Gadolinium(III) Complex for In Vivo Imaging of Amyloid-β in an Alzheimer's Disease Mouse Model

X Wang, HN Chan, N Desbois, CP Gros… - … Applied Materials & …, 2021 - ACS Publications
Despite the wide use of magnetic resonance imaging (MRI) as a clinical diagnostic tool,
there are still no clinically approved MRI contrast agents that can be applied for cerebral …

Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation

X Wang, C Wang, HN Chan, I Ashok… - Talanta, 2021 - Elsevier
To enable the early detection and intervention of Alzheimer's disease (AD), it is highly
desirable to develop novel theranostic agents for simultaneous detection of toxic and …

[HTML][HTML] Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification

HN Chan, D Xu, SL Ho, D He, MS Wong, HW Li - Theranostics, 2019 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), a chronic neurodegenerative disease associated with the
loss of neurons in the brain, is the most pervasive type of dementia; 47 million people are …