Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

EH Sohn, HW van Dijk, C Jiao… - Proceedings of the …, 2016 - National Acad Sciences
Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal
diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in …

[HTML][HTML] Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy

HW Van Dijk, PHB Kok, M Garvin… - … & visual science, 2009 - iovs.arvojournals.org
purpose. To determine whether type 1 diabetes preferentially affects the inner retinal layers
by comparing the thickness of six retinal layers in type 1 diabetic patients who have no or …

[HTML][HTML] Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes

HW Van Dijk, FD Verbraak, PHB Kok… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: To determine which retinal layers are most affected by diabetes and contribute to
thinning of the inner retina and to investigate the relationship between retinal layer thickness …

[HTML][HTML] Early neurodegeneration in the retina of type 2 diabetic patients

HW Van Dijk, FD Verbraak, PHB Kok… - … & visual science, 2012 - jov.arvojournals.org
Purpose.: The purpose of this study was to determine whether diabetes type 2 causes
thinning of retinal layers as a sign of neurodegeneration and to investigate the possible …

[HTML][HTML] Effect of age on individual retinal layer thickness in normal eyes as measured with spectral-domain optical coherence tomography

N Demirkaya, HW Van Dijk… - … & visual science, 2013 - tvst.arvojournals.org
Purpose.: To determine the effect of age on the thickness of individual retinal layers,
measured with spectral-domain optical coherence tomography (SD-OCT), in a population of …

[HTML][HTML] Association of visual function and ganglion cell layer thickness in patients with diabetes mellitus type 1 and no or minimal diabetic retinopathy

HW van Dijk, FD Verbraak, M Stehouwer, PHB Kok… - Vision research, 2011 - Elsevier
Diabetic retinopathy (DR) classically presents with micro-aneurysms, small haemorrhages
and/or lipoprotein exudates. Several studies have indicated that neural loss occurs in DR …

The relationship between the optical density of cataract and its influence on retinal nerve fibre layer thickness measured with spectral domain optical coherence …

PHB Kok, TJTP van den Berg, HW van Dijk… - Acta …, 2013 - Wiley Online Library
Purpose: The purpose of this study was to model the influence of cataract on Spectral
Domain Optical Coherence Tomography (SDOCT) image quality and Retinal Nerve Fibre …

[HTML][HTML] A model for the effect of disturbances in the optical media on the OCT image quality

PHB Kok, HW van Dijk… - … & visual science, 2009 - jov.arvojournals.org
purpose. The loss of quality of optical coherence tomography (OCT) images resulting from
disturbances in the optical media has been modeled. methods. OCT measurements were …

Variability in photocoagulation treatment of diabetic macular oedema

HW van Dijk, FD Verbraak, PHB Kok… - Acta …, 2013 - Wiley Online Library
Purpose: To establish whether differences in the assessment of diabetic macular oedema
(DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead …

[PDF][PDF] Decreased retinal ganglion cell layer thickness in type 1 diabetic patients

HW van Dijk, FD Verbraak, PHB Kok, MK Garvin… - Shedding new light on … - dare.uva.nl
Purpose: To determine which retinal layers are most affected by diabetes and contribute to
thinning of the inner retina, and to investigate the relationship between retinal layer …