Definition of glaucoma: clinical and experimental concepts
Glaucoma is a term describing a group of ocular disorders with multi‐factorial etiology united
by a clinically characteristic intraocular pressure‐associated optic neuropathy. It is not a …
by a clinically characteristic intraocular pressure‐associated optic neuropathy. It is not a …
Primary open-angle glaucoma
RN Weinreb, CKS Leung, JG Crowston… - Nature reviews Disease …, 2016 - nature.com
Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …
[HTML][HTML] Association between digital smart device use and myopia: a systematic review and meta-analysis
Background Excessive use of digital smart devices, including smartphones and tablet
computers, could be a risk factor for myopia. We aimed to review the literature on the …
computers, could be a risk factor for myopia. We aimed to review the literature on the …
Oxidative stress and mitochondrial dysfunction in glaucoma
V Chrysostomou, F Rezania, IA Trounce… - Current opinion in …, 2013 - Elsevier
Mitochondrial dysfunction increases reactive oxygen species (ROS) production and when
this overwhelms the cellular antioxidant defences, oxidative stress ensues. Oxidative stress …
this overwhelms the cellular antioxidant defences, oxidative stress ensues. Oxidative stress …
Mitochondrial dysfunction and glaucoma
GYX Kong, NJ Van Bergen, IA Trounce… - Journal of …, 2009 - journals.lww.com
Glaucoma is increasingly recognized as a neurodegenerative disorder, characterized by the
accelerated loss of retinal ganglion cells (RGCs) and their axons. Open angle glaucoma …
accelerated loss of retinal ganglion cells (RGCs) and their axons. Open angle glaucoma …
Vascular risk factors in glaucoma: a review
Glaucoma, one of the major causes of blindness in the world, is a progressive optic
neuropathy. Elevated intraocular pressure is a well‐known major risk factor for glaucoma. In …
neuropathy. Elevated intraocular pressure is a well‐known major risk factor for glaucoma. In …
A pilot study of a system for grading of drainage blebs after glaucoma surgery
AP Wells, JG Crowston, J Marks, JF Kirwan… - Journal of …, 2004 - journals.lww.com
Purpose: To develop and evaluate a novel bleb grading scheme for clinical and
photographic evaluation. Method: A system for grading bleb photographs using widely …
photographic evaluation. Method: A system for grading bleb photographs using widely …
[HTML][HTML] Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease
Studies of rodent models of Alzheimer's disease (AD) and of human tissues suggest that the
retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve …
retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve …
[HTML][HTML] Recharacterization of the RGC-5 retinal ganglion cell line
purpose. The transformed RGC-5 retinal ganglion cell line is used widely in glaucoma
research. Increased resistance to glutamate was noted in published literature and led to the …
research. Increased resistance to glutamate was noted in published literature and led to the …
Optic disk size and glaucoma
EM Hoffmann, LM Zangwill, JG Crowston… - Survey of …, 2007 - Elsevier
Assessment of optic disk size is an important, but often overlooked, component of the
diagnostic evaluation for glaucoma. Measured values of optic disk size vary with the …
diagnostic evaluation for glaucoma. Measured values of optic disk size vary with the …