The DNA damage response (DDR), through the action of sensors, transducers, and
effectors, orchestrates the appropriate repair of DNA damage and resolution of DNA …

Acne is one of the most common disorders treated by dermatologists and other health care
providers. While it most often affects adolescents, it is not uncommon in adults and can also …

Over the past two decades, the molecular machinery that underlies autophagic responses
has been characterized with ever increasing precision in multiple model organisms …

The cyclin-dependent kinase CdkP associates with cyclins A, D, and E and has been
implicated in the control of the Gl to S phase transition in mammals. To identify potential …

The tumor growth suppressor WAF1/CIP1 was recently shown to be induced by p53 and to
be a potent inhibitor of cyclin-dependent kinases. In the present studies, we sought to …

To initiate studies on how protein-protein interaction (or “interactome”) networks relate to
multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans …

p21CIP11WAF1 is a CDK Inhibitor regulated by the tumor suppressor p53 and is
hypothesized to mediate G1 arrest. p53 has been suggested to derive anti-oncogenic …

The first chapter is concerned with experiments, analogies and models. There are sections
on dispersal, dormancy and recruitment of seedling populations, effects of neighbours …

This text book presents an integrated study of plant and animal ecology with mathematical
and laboratory studies described where necessary. Examples drawn from real ecological …

Abstract γ-Irradiation of human diploid fibroblasts in the G1 interval caused arrest of the cell
cycle prior to S phase. This cell cycle block was correlated with a lack of activation of both …