User profiles for "author:J Lochhead"

Jeffrey James Lochhead

Research Assistant Professor, University of Arizona
Verified email at arizona.edu
Cited by 3378

Intranasal delivery of biologics to the central nervous system

JJ Lochhead, RG Thorne - Advanced drug delivery reviews, 2012 - Elsevier
Treatment of central nervous system (CNS) diseases is very difficult due to the blood–brain
barrier's (BBB) ability to severely restrict entry of all but small, non-polar compounds …

[HTML][HTML] Structure, function, and regulation of the blood-brain barrier tight junction in central nervous system disorders

JJ Lochhead, J Yang, PT Ronaldson… - Frontiers in physiology, 2020 - frontiersin.org
The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy
critical to neuronal function while simultaneously excluding neurotoxic substances from the …

[HTML][HTML] Perivascular and perineural pathways involved in brain delivery and distribution of drugs after intranasal administration

JJ Lochhead, TP Davis - Pharmaceutics, 2019 - mdpi.com
One of the most challenging aspects of treating disorders of the central nervous system
(CNS) is the efficient delivery of drugs to their targets within the brain. Only a small fraction of …

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results

…, D Wasser, S Johnson-Traver, J Lochhead… - Archives of …, 2005 - jamanetwork.com
Background Laboratory evidence of cholesterol-induced production of amyloid β as a
putative neurotoxin precipitating Alzheimer disease, along with epidemiological evidence …

[BOOK][B] Problem solving & comprehension

A Whimbey, J Lochhead, R Narode - 2013 - taylorfrancis.com
This popular book shows students how to increase their power to analyze problems and
comprehend what they read using the Think Aloud Pair Problem Solving [TAPPS] method …

Translation difficulties in learning mathematics

J Clement, J Lochhead, GS Monk - The American Mathematical …, 1981 - Taylor & Francis
1981] MATHEMATICAL EDUCATION 287 of written tests and of interviews suggest that the
modeling process is far more complex than is generally imagined. In fact, rather than being …

Oxidative stress increases blood–brain barrier permeability and induces alterations in occludin during hypoxia–reoxygenation

JJ Lochhead, G McCaffrey, CE Quigley… - Journal of Cerebral …, 2010 - journals.sagepub.com
The blood–brain barrier (BBB) has a critical role in central nervous system homeostasis.
Intercellular tight junction (TJ) protein complexes of the brain microvasculature limit …

Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration

JJ Lochhead, DJ Wolak, ME Pizzo… - Journal of Cerebral …, 2015 - journals.sagepub.com
The intranasal administration route is increasingly being used as a noninvasive method to
bypass the blood—brain barrier because evidence suggests small fractions of nasally …

[BOOK][B] Postmodern music/postmodern thought

J Lochhead, J Auner - 2013 - taylorfrancis.com
What is postmodern music and how does it differ from earlier styles, including modernist
music? What roles have electronic technologies and sound production played in defining …

Student Conceptions of Simple Circuits.

N Fredette, J Lochhead - Physics Teacher, 1980 - ERIC
ERIC - EJ224278 - Student Conceptions of Simple Circuits., Physics Teacher, 1980-Mar
NotesFAQContact Us ERIC - Institute of Education Sciences Collection Thesaurus Advanced …