Aetiological and immunological aspects of AMD, a leading cause of blindness in Western
countries, have been reviewed. Developmental studies suggest that anatomical features …

Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

Human and macaque retinae have similar retinal vascular anatomy. The general features of
the retinal vascular anatomy of these two primates have much in common with more widely …

Geographic atrophy (GA), an untreatable advanced form of age-related macular
degeneration, results from retinal pigmented epithelium (RPE) cell degeneration. Here we …

Presence of a fovea centralis is directly linked to molecular specification of an avascular
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …

The central retina in primates is adapted for high acuity vision. The most significant
adaptations to neural retina in this respect are: 1. The very high density of cone …

Neurogenesis in the ventricular layer and the development of cell topography in the
ganglion cell layer have been studied in whole‐mounts of human fetal retinae. At the end of …

We have estimated the number of axons in the optic nerves of human fetuses ranging in
gestational age from approximately 10 to 33 weeks. At 10–12 weeks of gestation there were …

The formation of the primate fovea has fascinated a substantial number of histologists,
pathologists, ophthalmologists and physiologists for more than a century. In this article …

Whilst animal studies and a pilot clinical trial suggest that intravitreal triamcinolone
acetonide (TA) may be useful in the treatment of age-related macular degeneration (AMD) …