User profiles for "author:J M Seddon"
John M SeddonVerified email at imperial.ac.uk Cited by 11659 |
Age-related macular degeneration
Age-related macular degeneration is a major cause of blindness worldwide. With ageing
populations in many countries, more than 20% might have the disorder. Advanced age …
populations in many countries, more than 20% might have the disorder. Advanced age …
Structure of the inverted hexagonal (HII) phase, and non-lamellar phase transitions of lipids
JM Seddon - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1990 - Elsevier
IV Thermodynarmcs of non-lamellar phase transitions A Lipid self-assembly and the
hydrophoblc effect B Intermolecular Interactions C Interfaclal curvature D Lateral expansion …
hydrophoblc effect B Intermolecular Interactions C Interfaclal curvature D Lateral expansion …
Epidemiologic aspects of uveal melanoma
KM Egan, JM Seddon, RJ Glynn, ES Gragoudas… - Survey of …, 1988 - Elsevier
Although the underlying cause or causes of uveal melanoma have yet to be elucidated,
important insights may be gained by examining the epidemiologic features of the disease …
important insights may be gained by examining the epidemiologic features of the disease …
Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration
JM Seddon, UA Ajani, RD Sperduto, R Hiller, N Blair… - Jama, 1994 - jamanetwork.com
Objective.—To evaluate the relationships between dietary intake of carotenoids and
vitamins A, C, and E and the risk of neovascular age-related macular degeneration (AMD) …
vitamins A, C, and E and the risk of neovascular age-related macular degeneration (AMD) …
Mutation of the Stargardt Disease Gene (ABCR) in Age-Related Macular Degeneration
R Allikmets, NF Shroyer, N Singh, JM Seddon… - Science, 1997 - science.org
Age-related macular degeneration (AMD) is the leading cause of severe central visual
impairment among the elderly and is associated both with environmental factors such as …
impairment among the elderly and is associated both with environmental factors such as …
Cancer incidence after retinoblastoma: radiation dose and sarcoma risk
FL Wong, JD Boice, DH Abramson, RE Tarone… - Jama, 1997 - jamanetwork.com
Context.—There is a substantial risk of a second cancer for persons with hereditary
retinoblastoma, which is enhanced by radiotherapy. Objective.—To examine long-term risk …
retinoblastoma, which is enhanced by radiotherapy. Objective.—To examine long-term risk …
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
Age-related macular degeneration (AMD) is a common, late-onset disease with seemingly
typical complexity: recurrence ratios for siblings of an affected individual are three-to sixfold …
typical complexity: recurrence ratios for siblings of an affected individual are three-to sixfold …
Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration
W Chen, D Stambolian, AO Edwards… - Proceedings of the …, 2010 - National Acad Sciences
We executed a genome-wide association scan for age-related macular degeneration (AMD)
in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH (P< …
in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH (P< …
The incidence of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses
The wearing of contact lenses has increased dramatically in the past decade; over 4 million
people in the United States now use extended-wear soft contact lenses, and 9 million use …
people in the United States now use extended-wear soft contact lenses, and 9 million use …
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
BM Neale, J Fagerness, R Reynolds… - Proceedings of the …, 2010 - National Acad Sciences
Advanced age-related macular degeneration (AMD) is the leading cause of late onset
blindness. We present results of a genome-wide association study of 979 advanced AMD …
blindness. We present results of a genome-wide association study of 979 advanced AMD …