Myopia

PN Baird, SM Saw, C Lanca, JA Guggenheim… - Nature reviews Disease …, 2020 - nature.com
Myopia, also known as short-sightedness or near-sightedness, is a very common condition
that typically starts in childhood. Severe forms of myopia (pathologic myopia) are associated …

[HTML][HTML] IMI risk factors for myopia

IG Morgan, PC Wu, LA Ostrin… - … & visual science, 2021 - iovs.arvojournals.org
Risk factor analysis provides an important basis for developing interventions for any
condition. In the case of myopia, evidence for a large number of risk factors has been …

[HTML][HTML] IMI prevention of myopia and its progression

JB Jonas, M Ang, P Cho… - … & visual science, 2021 - iovs.arvojournals.org
The prevalence of myopia has markedly increased in East and Southeast Asia, and
pathologic consequences of myopia, including myopic maculopathy and high myopia …

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

VJM Verhoeven, PG Hysi, R Wojciechowski, Q Fan… - Nature …, 2013 - nature.com
Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

[HTML][HTML] Time outdoors and physical activity as predictors of incident myopia in childhood: a prospective cohort study

JA Guggenheim, K Northstone… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: Timespent in “sports/outdoor activity” has shown a negative association with
incident myopia during childhood. We investigated the association of incident myopia with …

[HTML][HTML] IMI–interventions for controlling myopia onset and progression report

CF Wildsoet, A Chia, P Cho… - … & visual science, 2019 - iovs.arvojournals.org
Myopia has been predicted to affect approximately 50% of the world's population based on
trending myopia prevalence figures. Critical to minimizing the associated adverse visual …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Update and guidance on management of myopia. European Society of Ophthalmology in cooperation with International Myopia Institute

J Németh, B Tapasztó, WA Aclimandos… - European Journal …, 2021 - journals.sagepub.com
The prevalence of myopia is increasing extensively worldwide. The number of people with
myopia in 2020 is predicted to be 2.6 billion globally, which is expected to rise up to 4.9 …

Form-deprivation myopia induces activation of scleral matrix metalloproteinase-2 in tree shrew.

JA Guggenheim, NA McBrien - Investigative ophthalmology & …, 1996 - iovs.arvojournals.org
PURPOSE: To investigate whether structural changes to the sclera during form-deprivation
myopia are caused by active tissue remodeling, the gelatinase activity of tree shrew scleras …

Education and myopia: assessing the direction of causality by mendelian randomisation

E Mountjoy, NM Davies, D Plotnikov, GD Smith… - bmj, 2018 - bmj.com
Objectives To determine whether more years spent in education is a causal risk factor for
myopia, or whether myopia is a causal risk factor for more years in education. Design …