Recent advances have driven the development of stem cell-derived, self-organizing, three-
dimensional miniature organs, termed organoids, which mimic different eye tissues …

Purpose.: To compare intraocular pressure (IOP) measurements obtained using the
Topocon noncontact tonometer (NCT), the Goldmann applanation tonometer (GAT), and the …

Purpose: To investigate the applicability of a newly developed corneal topographer in
assessing tear film stability. Methods: This is a prospective, case–control study. Forty-four …

Therapeutic genome editing requires effective and targeted delivery methods. The delivery
of Cas9 mRNA using adeno-associated viruses has led to potent in vivo therapeutic efficacy …

Herpes simplex virus type 1 (HSV-1) is a leading cause of infectious blindness. Current
treatments for HSV-1 do not eliminate the virus from the site of infection or latent reservoirs in …

Summary Nonsense mutations, accounting for> 20% of disease-associated mutations, lead
to premature translation termination. Replacing uridine with pseudouridine in stop codons …

The therapeutic potential of nanomaterials toward oxidative damage relevant diseases has
attracted great attentions by offering promising advantages compared with conventional …

Background Dry eye syndrome (DES) is a common ocular disorder occurring in general
population. The purpose of this study is to evaluate the impact of DES on vision-related …

Purpose To investigate the features of corneal epithelial thickness topography with Fourier-
domain optical coherence tomography (OCT) in dry eye patients. Methods In this cross …

Allergic conjunctivitis is a common problem that significantly impairs patients' quality of life.
Whether air pollution serves as a risk factor for the development of allergic conjunctivitis …