OCT angiography in optic disc drusen: comparison with structural and functional parameters

H Engelke, M Shajari, J Riedel, N Mohr… - British Journal of …, 2020 - bjo.bmj.com
Background Optic disc drusen (ODD) can cause retinal nerve fibre layer (RNFL) defects with
progressive visual field (VF) loss. Microvascular changes are discussed as a cause. We …

[HTML][HTML] The influence of ultra-low tidal volume ventilation during cardiopulmonary resuscitation on renal and hepatic end-organ damage in a porcine model

K Mohnke, V Buschmann, T Baller, J Riedel, M Renz… - Biomedicines, 2023 - mdpi.com
The optimal ventilation strategy during cardiopulmonary resuscitation (CPR) has eluded
scientists for years. This porcine study aims to validate the hypothesis that ultra-low tidal …

[HTML][HTML] High PEEP levels during CPR improve ventilation without deleterious haemodynamic effects in pigs

M Renz, L Müllejans, J Riedel, K Mohnke… - Journal of Clinical …, 2022 - mdpi.com
Background: Invasive ventilation during cardiopulmonary resuscitation (CPR) is very
complex due to unique thoracic pressure conditions. Current guidelines do not provide …

[HTML][HTML] Resveratrol influences pulmonary mechanics and inflammatory response in a porcine ARDS model

R Rissel, L Kirchner, M Renz, K Mohnke, J Riedel… - Life Sciences, 2023 - Elsevier
Aims Influencing the inflammatory response represents an important branch in ARDS
research. The naturally occurring polyphenol derivative resveratrol has already been …

[HTML][HTML] The Impact of Transfer-Related Ischemia on Free Flap Metabolism and Electrolyte Homeostasis—A New In Vivo Experimental Approach in Pigs

D Stephan, S Blatt, J Riedel, K Mohnke… - Journal of Clinical …, 2023 - mdpi.com
Free flap tissue transfer represents the gold standard for extensive defect reconstruction,
although malperfusion due to thrombosis remains the leading risk factor for flap failure …

[HTML][HTML] Analysis of cerebral Interleukin-6 and tumor necrosis factor alpha patterns following different ventilation strategies during cardiac arrest in pigs

M Renz, L Müller, M Herbst, J Riedel, K Mohnke… - PeerJ, 2023 - peerj.com
Hypoxia-induced neuroinflammation after cardiac arrest has been shown to be mitigated by
different ventilation methods. In this prospective randomized animal trial, 35 landrace pigs …

[HTML][HTML] Ultra-low tidal volume ventilation during cardiopulmonary resuscitation shows no mitigating effect on pulmonary end-organ damage compared to standard …

K Mohnke, P Conzelmann, M Renz, J Riedel… - Intensive Care Medicine …, 2023 - Springer
Objective This study aimed to determine whether ultra-low tidal volume ventilation (ULTVV)
applied during cardiopulmonary resuscitation (CPR) compared with standard ventilation …

Author Spotlight: Induction of Experimental Endotoxemic Shock in Pigs for Studying Hemodynamic and Respiratory Failure

A Urmann, K Mohnke, J Riedel, J Hain, M Renz… - JoVE (Journal of …, 2023 - jove.com
Sepsis and septic shock are frequently encountered in patients treated in intensive care
units (ICUs) and are among the leading causes of death in these patients. It is caused by a …

[HTML][HTML] Synchronized ventilation during resuscitation in pigs does not necessitate high inspiratory pressures to provide adequate oxygenation

M Renz, RRC Noack, R Rissel, K Mohnke… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Synchronized ventilation during resuscitation in pigs does not necessitate high inspiratory
pressures to provide adequate oxygenation - PMC Back to Top Skip to main content NIH NLM …

Unfinished business: Terminated cancer trials and the relevance of treatment intent, sponsors and intervention types

D Buergy, J Riedel, GR Sarria… - … Journal of Cancer, 2021 - Wiley Online Library
The aim of the study was to report on the association of trial sponsors with intervention type,
treatment intent, recruitment success and reasons to terminate cancer trials. The …