[HTML][HTML] Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation
S Shibahara, K Takeda, K Yasumoto, T Udono… - Journal of Investigative …, 2001 - Elsevier
Microphthalmia-associated transcription factor (MITF) regulates the differentiation and
development of melanocytes and retinal pigment epithelium and is also responsible for …
development of melanocytes and retinal pigment epithelium and is also responsible for …
[PDF][PDF] Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
Y Minegishi, M Saito, T Morio, K Watanabe… - Immunity, 2006 - cell.com
Summary Tyrosine kinase 2 (Tyk2) is a nonreceptor tyrosine kinase that belongs to the
Janus kinase (Jak) family. Here we identified a homozygous Tyk2 mutation in a patient who …
Janus kinase (Jak) family. Here we identified a homozygous Tyk2 mutation in a patient who …
[HTML][HTML] Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a
Microphthalmia-associated transcription factor (Mitf) plays a critical role in the development
of neural crest-derived melanocytes. Here, we show that exogenously added Wnt-3a …
of neural crest-derived melanocytes. Here, we show that exogenously added Wnt-3a …
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
M Nishio, K Watanabe, J Sasaki, C Taya… - Nature cell …, 2007 - nature.com
Proper neutrophil migration into inflammatory sites ensures host defense without tissue
damage. Phosphoinositide 3-kinase (PI (3) K) and its lipid product phosphatidylinositol 3, 4 …
damage. Phosphoinositide 3-kinase (PI (3) K) and its lipid product phosphatidylinositol 3, 4 …
Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity
R Kosaki, K Watanabe, Y Yamaguchi - Cancer research, 1999 - AACR
Hyaluronan (HA) has long been implicated in malignant transformation and tumor
progression. However, due to the lack of molecular tools to directly manipulate production of …
progression. However, due to the lack of molecular tools to directly manipulate production of …
[HTML][HTML] Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells
H Takai, M Kanematsu, K Yano, E Tsuda… - Journal of Biological …, 1998 - ASBMB
Osteoprotegerin (OPG)/osteoclastogenesis inhibitory factor (OCIF) is a recently identified
cytokine that belongs to the tumor necrosis factor receptor superfamily and regulates bone …
cytokine that belongs to the tumor necrosis factor receptor superfamily and regulates bone …
[HTML][HTML] Microphthalmia‐associated transcription factor interacts with LEF‐1, a mediator of Wnt signaling
K Yasumoto, K Takeda, H Saito, K Watanabe… - The EMBO …, 2002 - embopress.org
Wnt signals regulate differentiation of neural crest cells through the β‐catenin associated
with a nuclear mediator of the lymphoid‐enhancing factor 1 (LEF‐1)/T‐cell factors (TCFs) …
with a nuclear mediator of the lymphoid‐enhancing factor 1 (LEF‐1)/T‐cell factors (TCFs) …
[HTML][HTML] Current methods for body fluid identification related to sexual crime: focusing on saliva, semen, and vaginal fluid
K Sakurada, K Watanabe, T Akutsu - Diagnostics, 2020 - mdpi.com
Although, DNA typing plays a decisive role in the identification of persons from blood and
body fluid stains in criminal investigations, clarifying the origin of extracted DNA has also …
body fluid stains in criminal investigations, clarifying the origin of extracted DNA has also …
[HTML][HTML] SORL1 Is Genetically Associated with Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a
3-stage genome-wide association study (GWAS) using three populations: Japanese from …
3-stage genome-wide association study (GWAS) using three populations: Japanese from …
Novel mutations in the connexin 26 gene (GJB2) responsible for childhood deafness in the Japanese population
T Kudo, K Ikeda, S Kure, Y Matsubara… - American journal of …, 2000 - Wiley Online Library
Mutations in the connexin 26 gene (GJB2), which encodes a gap‐junction protein and is
expressed in the inner ear, have been shown to be responsible for a major part of …
expressed in the inner ear, have been shown to be responsible for a major part of …