User profiles for "author:Kunal Malik"
 | Kunal MalikIcahn School of Medicine at Mount Sinai Verified email at downstate.edu Cited by 1806 |
An update on the pathophysiology of atopic dermatitis
K Malik, KD Heitmiller, T Czarnowicki - Dermatologic Clinics, 2017 - derm.theclinics.com
AD is a complex, multifactorial disease. Immune dysregulation, barrier impairment, microbial
shifts, environmental factors, and genetic propensity all orchestrate the disease phenotype …
shifts, environmental factors, and genetic propensity all orchestrate the disease phenotype …
[HTML][HTML] Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by …
Background Interleukin 22 promotes epidermal hyperplasia and inhibits skin barrier
function. Objective Evaluate interleukin 22 blockade in adults with moderate-to-severe …
function. Objective Evaluate interleukin 22 blockade in adults with moderate-to-severe …
Leiomyoma cutis: a focused review on presentation, management, and association with malignancy
K Malik, P Patel, J Chen, A Khachemoune - American journal of clinical …, 2015 - Springer
Cutaneous leiomyomas (CLs) are rare, sporadic, or inherited tumors of smooth muscle
origin associated with various disorders. Hereditary leiomyomatosis and renal cell cancer …
origin associated with various disorders. Hereditary leiomyomatosis and renal cell cancer …
[HTML][HTML] The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins
Beyond classic “allergic”/atopic comorbidities, atopic dermatitis (AD) emerges as systemic
disease with increased cardiovascular risk. To better define serum inflammatory and …
disease with increased cardiovascular risk. To better define serum inflammatory and …
Lynch Syndrome and Muir-Torre Syndrome: An update and review on the genetics, epidemiology, and management of two related disorders
Hereditary Nonpolyposis Colorectal Cancer (HNPCC), also known as Lynch Syndrome, is
an autosomal dominant, tumor predisposing disorder usuallycaused by germline mutations …
an autosomal dominant, tumor predisposing disorder usuallycaused by germline mutations …
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab
Background IL-22 is potentially a pathogenic cytokine in patients with atopic dermatitis (AD),
but the molecular effects of IL-22 antagonism have not been defined in human subjects …
but the molecular effects of IL-22 antagonism have not been defined in human subjects …
[HTML][HTML] Uveal metastasis: clinical features and survival outcome of 2214 tumors in 1111 patients based on primary tumor origin
CL Shields, RJ Welch, K Malik… - Middle East African …, 2018 - journals.lww.com
PURPOSE: The purpose of this study is to evaluate patients with uveal metastasis based on
primary tumor site. METHODS: Retrospective analysis from Wills Eye Hospital, Philadelphia …
primary tumor site. METHODS: Retrospective analysis from Wills Eye Hospital, Philadelphia …
[HTML][HTML] A phase 2 randomized trial of apremilast in patients with atopic dermatitis
A phase 2, double-blind, placebo-controlled trial evaluated apremilast efficacy, safety, and
pharmacodynamics in adults with moderate to severe atopic dermatitis. Patients were …
pharmacodynamics in adults with moderate to severe atopic dermatitis. Patients were …
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis
Background Atopic dermatitis (AD) shows differential clinical presentation in older compared
with younger patients. Nevertheless, changes in the AD molecular profile with age are …
with younger patients. Nevertheless, changes in the AD molecular profile with age are …
Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature
K Malik, H He, TN Huynh, G Tran, K Mueller… - Journal of Allergy and …, 2019 - Elsevier
Background Ichthyoses are a group of rare skin disorders lacking effective treatments.
Although genetic mutations are progressively delineated, comprehensive molecular …
Although genetic mutations are progressively delineated, comprehensive molecular …