The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …

The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water
transport across the plasma membranes of cells in response to osmotic gradients. Data from …

Abstract Aquaporin-4 (AQP4) is a water-channel protein expressed strongly in the brain,
predominantly in astrocyte foot processes at the borders between the brain parenchyma and …

Abstract Aquaporin-1 (AQP1) is a water channel protein expressed widely in vascular
endothelia, where it increases cell membrane water permeability,,. The role of AQP1 in …

ABSTRACT Aquaporin‐4 (AQP4) is the major water channel in the brain, expressed
predominantly in astroglial cell membranes. Initial studies in AQP4‐deficient mice showed …

Neuromyelitis optica is an inflammatory demyelinating disorder of the CNS. The discovery of
circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) …

Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system
associated with autoantibodies against the glial water channel protein aquaporin-4. It has …

Aquaporin (AQP) water channels are expressed primarily in cell plasma membranes. In this
paper, we review recent evidence that AQPs facilitate cell migration. AQP-dependent cell …

About 80% of the brain is water. This review discusses the importance of the three brain
water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is expressed in the …

Aquaporin-4, the major water-selective channel in astroglia throughout the central nervous
system, facilitates water movement into and out of the brain. Here, we identify a novel role for …