User profiles for "author:Marcello Allegretti"
Marcello AllegrettiDompé Farmaceutici spa Verified email at dompe.com Cited by 5598 |
ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets
C Bizzarri, AR Beccari, R Bertini, MR Cavicchia… - Pharmacology & …, 2006 - Elsevier
ELR+ CXC chemokines, by direct interaction with their cell surface receptors CXC
chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to …
chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to …
[HTML][HTML] The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress …
MC Cesta, M Zippoli, C Marsiglia, EM Gavioli… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis
MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …
[PDF][PDF] CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz… - Immunity, 2020 - cell.com
Neutrophils are expanded and abundant in cancer-bearing hosts. Under the influence of
CXCR1 and CXCR2 chemokine receptor agonists and other chemotactic factors produced …
CXCR1 and CXCR2 chemokine receptor agonists and other chemotactic factors produced …
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury
R Bertini, M Allegretti, C Bizzarri… - Proceedings of the …, 2004 - National Acad Sciences
The chemokine CXC ligand 8 (CXCL8)/IL-8 and related agonists recruit and activate
polymorphonuclear cells by binding the CXC chemokine receptor 1 (CXCR1) and CXCR2 …
polymorphonuclear cells by binding the CXC chemokine receptor 1 (CXCR1) and CXCR2 …
Tumor-produced interleukin-8 attracts human myeloid-derived suppressor cells and elicits extrusion of neutrophil extracellular traps (NETs)
C Alfaro, A Teijeira, C Oñate, G Perez… - Clinical Cancer …, 2016 - AACR
Purpose: Myeloid-derived suppressor cells (MDSC) are considered an important T-cell
immunosuppressive component in cancer-bearing hosts. The factors that attract these cells …
immunosuppressive component in cancer-bearing hosts. The factors that attract these cells …
[HTML][HTML] Phase II randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis
S Bonini, A Lambiase, P Rama, F Sinigaglia… - Ophthalmology, 2018 - Elsevier
Purpose To evaluate the safety and efficacy of topical recombinant human nerve growth
factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare …
factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare …
[HTML][HTML] Topical recombinant human nerve growth factor (cenegermin) for neurotrophic keratopathy: a multicenter randomized vehicle-controlled pivotal trial
SC Pflugfelder, M Massaro-Giordano, VL Perez… - Ophthalmology, 2020 - Elsevier
Purpose To evaluate the efficacy and safety of topical cenegermin (recombinant human
nerve growth factor) in patients with neurotrophic keratopathy. Design Multicenter …
nerve growth factor) in patients with neurotrophic keratopathy. Design Multicenter …
[HTML][HTML] CXCR1/2 inhibition enhances pancreatic islet survival after transplantation
A Citro, E Cantarelli, P Maffi, R Nano… - The Journal of …, 2012 - Am Soc Clin Investig
Although long considered a promising treatment option for type 1 diabetes, pancreatic islet
cell transformation has been hindered by immune system rejection of engrafted tissue. The …
cell transformation has been hindered by immune system rejection of engrafted tissue. The …
[HTML][HTML] LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells
L Sturla, C Fresia, L Guida, S Bruzzone, S Scarfì… - Journal of Biological …, 2009 - ASBMB
Abscisic acid (ABA) is a plant hormone regulating fundamental physiological functions in
plants, such as response to abiotic stress. Recently, ABA was shown to be produced and …
plants, such as response to abiotic stress. Recently, ABA was shown to be produced and …