Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

For decades intravitreal chemotherapy (IViC) remained virtually banished from the
therapeutic armamentarium against retinoblastoma, except as a heroic attempt of salvage …

Background Tumour control of vitreous seeds remains challenging owing to their resistance
to radiation and systemic chemotherapy. Objective To describe the short-term efficacy of …

Background The preservation of globe integrity has always been a major concern during the
treatment of retinoblastoma for fear of extraocular or metastatic spread. Intravitreal …

Background: Superselective ophthalmic artery chemotherapy (SOAC) has recently been
proposed as an alternative to intravenous chemoreduction for advanced intraocular …

Purpose To evaluate the clinical characteristics of the 3 classifications of vitreous seeds in
retinoblastoma—dust (class 1), spheres (class 2), and clouds (class 3)—and their responses …

Purpose.: To characterize in detail the phenotype of five unrelated families with autosomal
dominant bull's eye maculopathy (BEM) due to the R373C mutation in the PROM1 gene …

Purpose The introduction of intra-arterial chemotherapy (IAC) as salvage treatment has
improved the prognosis for eye conservation in group D retinoblastoma. The aim of this …

PURPOSE: To evaluate the efficacy of 106Ru plaque brachytherapy for the treatment of
retinoblastoma. METHODS AND MATERIALS: We reviewed a retrospective …

Background: Laser photocoagulation and cryotherapy to completely destroy telangiectatic
vessels and ischemic retina in Coats disease is barely applicable in advanced cases with …