User profiles for "author:Michael Nicolas"
michael nicolasDepartment of Plant Molecular Genetics, Centro Nacional de Biotecnología, Madrid Verified email at cnb.csic.es Cited by 1258 |
[HTML][HTML] Mechanisms of macular edema: beyond the surface
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …
occurs during the course of numerous retinal disorders and can cause severe impairment of …
TCP factors: new kids on the signaling block
Highlights•TCP factors play important roles in the modulation of phytohormone
signaling.•TCPs are involved in the synthesis of jasmonate, brassinosteroids, salicylic acid …
signaling.•TCPs are involved in the synthesis of jasmonate, brassinosteroids, salicylic acid …
Notch1 functions as a tumor suppressor in mouse skin
M Nicolas, A Wolfer, K Raj, JA Kummer, P Mill… - Nature …, 2003 - nature.com
Notch proteins are important in binary cell-fate decisions and inhibiting differentiation in
many developmental systems 1, and aberrant Notch signaling is associated with …
many developmental systems 1, and aberrant Notch signaling is associated with …
[HTML][HTML] Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A Rangarajan, C Talora, R Okuyama, M Nicolas… - The EMBO …, 2001 - embopress.org
The role of Notch signaling in growth/differentiation control of mammalian epithelial cells is
still poorly defined. We show that keratinocyte‐specific deletion of the Notch1 gene results in …
still poorly defined. We show that keratinocyte‐specific deletion of the Notch1 gene results in …
Oligopotent stem cells are distributed throughout the mammalian ocular surface
F Majo, A Rochat, M Nicolas, GA Jaoudé, Y Barrandon - Nature, 2008 - nature.com
The integrity of the cornea, the most anterior part of the eye, is indispensable for vision. Forty-
five million individuals worldwide are bilaterally blind and another 135 million have severely …
five million individuals worldwide are bilaterally blind and another 135 million have severely …
[HTML][HTML] Glucose-6-phosphate dehydrogenases: the hidden players of plant physiology
Glucose-6-phosphate dehydrogenase (G6PDH) catalyzes a metabolic hub between
glycolysis and the pentose phosphate pathway (PPP), which is the oxidation of glucose-6 …
glycolysis and the pentose phosphate pathway (PPP), which is the oxidation of glucose-6 …
Long-term renewal of hair follicles from clonogenic multipotent stem cells
S Claudinot, M Nicolas, H Oshima… - Proceedings of the …, 2005 - National Acad Sciences
Adult stem cells are essential for tissue renewal, regeneration, and repair, and their
expansion in culture is of paramount importance for regenerative medicine. Using the …
expansion in culture is of paramount importance for regenerative medicine. Using the …
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development
A Wolfer, T Bakker, A Wilson, M Nicolas… - Nature …, 2001 - nature.com
Notch proteins influence cell-fate decisions in many developing systems. Several gain-of-
function studies have suggested a critical role for Notch1 signaling in CD4-CD8 lineage …
function studies have suggested a critical role for Notch1 signaling in CD4-CD8 lineage …
[HTML][HTML] A gradual process of recombination restriction in the evolutionary history of the sex chromosomes in dioecious plants
To help understand the evolution of suppressed recombination between sex chromosomes,
and its consequences for evolution of the sequences of Y-linked genes, we have studied …
and its consequences for evolution of the sequences of Y-linked genes, we have studied …
[PDF][PDF] Comprehensive genetic landscape of uveal melanoma by whole-genome sequencing
B Royer-Bertrand, M Torsello, D Rimoldi… - The American Journal of …, 2016 - cell.com
Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma,
originates from melanocytes. To gain insights into its genetics, we performed whole-genome …
originates from melanocytes. To gain insights into its genetics, we performed whole-genome …