Background In patients with severe hemophilia B, gene therapy that is mediated by a novel
self-complementary adeno-associated virus serotype 8 (AAV8) vector has been shown to …

Age-related macular degeneration (AMD) is the leading cause of blindness and visual
disability in patients aged over 60 years in Europe and North America. 1 It is the third …

Dominant optic atrophy (DOA) is the commonest form of inherited optic neuropathy.
Although heterogeneous, a major locus has been mapped to chromosome 3q28 and the …

Leukocyte-endothelial interaction plays an important role in the early phase of the
development of diabetic retinopathy. It has been studied extensively linking inflammatory …

Age‐related macular maculopathy (ARM) and age‐related macular degeneration (AMD) are
the leading causes of blindness in the Western world. Despite the magnitude of this clinical …

Purpose Aflibercept has the potential advantage of reducing capacity problems by allowing
2 monthly visits for patients with neovascular macular degeneration (nAMD) compared with …

Objectives To collate available data via systematic review considering aetiology,
presentation and treatment of Uro-Symphyseal Fistula (USF) in order to inform a …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
industrial counties. Recent findings indicate that the autoimmunity is involved in the …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
industrial counties. Its pathogenesis is at least partially mediated by immunological factors …

Changes in higher order chromatin organisation have been linked to transcriptional
regulation; however, little is known about how such organisation alters during embryonic …