Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

Background Self management interventions help patients with chronic obstructive
pulmonary disease (COPD) acquire and practise the skills they need to carry out disease …

Background Chronic Obstructive Pulmonary Disease (COPD) self‐management
interventions should be structured but personalised and often multi‐component, with goals …

This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

Objective To determine the efficacy of oral morphine in relieving the sensation of
breathlessness in patients in whom the underlying aetiology is maximally treated. Design …

Background Palliative oxygen therapy is widely used for treatment of dyspnoea in
individuals with life-limiting illness who are ineligible for long-term oxygen therapy. We …

Background Lifetime lung function is related to quality of life and longevity. Over the lifespan,
individuals follow different lung function trajectories. Identification of these trajectories, their …

The efficiency of a standardised inhalation test procedure was studied by examining the
reproducibility of responses to histamine and methacholine. In addition, the responses to the …

CONTEXT: Randomized controlled trials can answer questions of efficacy, but long-term
pharmacovigilance studies generate complementary safety data. OBJECTIVES: Level I …

Allergen-induced late asthmatic responses are associated with an increase in bronchial
responsiveness to histamine. We have examined the relationship between the magnitude of …