User profiles for "author:P G Higgins"
Paul G HigginsUniversity of Cologne Verified email at uni-koeln.de Cited by 8430 |
[HTML][HTML] Heavy Metal Toxicity in Armed Conflicts Potentiates AMR in A. baumannii by Selecting for Antibiotic and Heavy Metal Co-resistance Mechanisms
W Bazzi, AG Abou Fayad, A Nasser… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii has become increasingly resistant to leading antimicrobial agents
since the 1970s. Increased resistance appears linked to armed conflicts, notably since …
since the 1970s. Increased resistance appears linked to armed conflicts, notably since …
Fluoroquinolones: structure and target sites
PG Higgins, AC Fluit, FJ Schmitz - Current drug targets, 2003 - ingentaconnect.com
The quinolones are a potent group of drugs that target the essential bacterial enzymes DNA
gyrase and topoisomerase IV. DNA gyrase is the primary target of Gram negative organisms …
gyrase and topoisomerase IV. DNA gyrase is the primary target of Gram negative organisms …
Global spread of carbapenem-resistant Acinetobacter baumannii
PG Higgins, C Dammhayn, M Hackel… - Journal of Antimicrobial …, 2010 - academic.oup.com
Objectives We have investigated the molecular epidemiology and distribution of
carbapenemase genes in 492 imipenem-non-susceptible Acinetobacter baumannii …
carbapenemase genes in 492 imipenem-non-susceptible Acinetobacter baumannii …
[HTML][HTML] Tracing the new SARS-CoV-2 variant BA. 2.86 in the community through wastewater surveillance in Bangkok, Thailand
DL Wannigama, M Amarasiri… - The Lancet Infectious …, 2023 - thelancet.com
(A) SARS-CoV-2 RNA concentration in wastewater at each BA. 2.86 positive locations from
June to July 2023.(B) Wastewater sampling location in Bangkok, Thailand, with colours …
June to July 2023.(B) Wastewater sampling location in Bangkok, Thailand, with colours …
Experimental parvoviral infection in humans
MJ Anderson, PG Higgins, LR Davis… - Journal of Infectious …, 1985 - academic.oup.com
Healthy adult volunteers were inoculated intranasally with human parvovirus obtained from
an asymptomatic blood donor. One week after inoculation, intense viremia was observed in …
an asymptomatic blood donor. One week after inoculation, intense viremia was observed in …
OXA-143, a Novel Carbapenem-Hydrolyzing Class D β-Lactamase in Acinetobacter baumannii
PG Higgins, L Poirel, M Lehmann… - Antimicrobial agents …, 2009 - Am Soc Microbiol
ABSTRACT A carbapenem-resistant Acinetobacter baumannii strain was isolated in Brazil in
2004 in which no known carbapenemase gene was detected by PCR. Cloning experiments …
2004 in which no known carbapenemase gene was detected by PCR. Cloning experiments …
OXA-235, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii
PG Higgins, FJ Pérez-Llarena, E Zander… - Antimicrobial agents …, 2013 - Am Soc Microbiol
We investigated the mechanism of carbapenem resistance in 10 Acinetobacter baumannii
strains isolated from the United States and Mexico between 2005 and 2009. The detection of …
strains isolated from the United States and Mexico between 2005 and 2009. The detection of …
Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007
Y Pfeifer, G Wilharm, E Zander… - Journal of …, 2011 - academic.oup.com
Objectives To investigate the genetic environment of the metallo-β-lactamase gene bla NDM-
1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods …
1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods …
Nosocomial bloodstream infections due to Acinetobacter baumannii, Acinetobacter pittii and Acinetobacter nosocomialis in the United States
H Wisplinghoff, T Paulus, M Lugenheim, D Stefanik… - Journal of Infection, 2012 - Elsevier
OBJECTIVES: To compare the clinical features and antimicrobial susceptibilities of the
clinically most important Acinetobacter species Acinetobacter baumannii, Acinetobacter pittii …
clinically most important Acinetobacter species Acinetobacter baumannii, Acinetobacter pittii …
Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-β-naphthylamide
S Pannek, PG Higgins, P Steinke… - Journal of …, 2006 - academic.oup.com
Abstract Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse
multidrug resistance (MDR) in Escherichia coli overexpressing RND-type efflux pumps but …
multidrug resistance (MDR) in Escherichia coli overexpressing RND-type efflux pumps but …