User profiles for "author:Pedram Hamrah"

Pedram Hamrah, MD

Professor of Ophthalmology, Tufts University School of Medicine
Verified email at tuftsmedicalcenter.org
Cited by 12153

TFOS DEWS II pain and sensation report

C Belmonte, JJ Nichols, SM Cox, JA Brock, CG Begley… - The ocular …, 2017 - Elsevier
Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

Corneal immunity is mediated by heterogeneous population of antigen-presenting cells

P Hamrah, SO Huq, Y Liu, Q Zhang… - Journal of Leucocyte …, 2003 - academic.oup.com
Corneal antigen-presenting cells (APC), including dendritic cells (DC), were thought to
reside exclusively in the peripheral cornea. Here, we present recent data from our group …

In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

[HTML][HTML] The corneal stroma is endowed with a significant number of resident dendritic cells

P Hamrah, Y Liu, Q Zhang… - … ophthalmology & visual …, 2003 - iovs.arvojournals.org
purpose. Dendritic cells (DCs) comprise a system of highly efficient antigen-presenting cells
(APCs) that initiate immune responses. The purpose of this study was to examine the normal …

[HTML][HTML] Novel characterization of MHC class II–negative population of resident corneal Langerhans cell–type dendritic cells

P Hamrah, Q Zhang, Y Liu… - … ophthalmology & visual …, 2002 - iovs.arvojournals.org
purpose. The presence of antigen-presenting cells (APCs) such as Langerhans cells (LCs),
an epithelial form of dendritic cells (DCs), in corneal tissue is critical for generation of …

Corneal sensation and subbasal nerve alterations in patients with herpes simplex keratitis: an in vivo confocal microscopy study

P Hamrah, A Cruzat, MH Dastjerdi, L Zheng… - Ophthalmology, 2010 - Elsevier
PURPOSE:: To study and correlate corneal sensation in patients with herpes simplex
keratitis (HSK) with density and morphologic features of subbasal corneal nerves by in vivo …

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision

C Cursiefen, L Chen, M Saint-Geniez… - Proceedings of the …, 2006 - National Acad Sciences
Transparency of the cornea, the window of the eye, is a prerequisite for vision. Angiogenesis
into the normally avascular cornea is incompatible with good vision and, therefore, the …

Twenty-five–year panorama of corneal immunology: emerging concepts in the immunopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal …

MR Dana, Y Qian, P Hamrah - Cornea, 2000 - journals.lww.com
Purpose. To describe the most recent advances in our understanding of the cellular and
molecular mechanisms involved in the immunopathogenesis of corneal …

Topical bevacizumab in the treatment of corneal neovascularization: results of a prospective, open-label, noncomparative study

MH Dastjerdi, KM Al-Arfaj, N Nallasamy… - Archives of …, 2009 - jamanetwork.com
Objective To study the safety and efficacy of topical bevacizumab in the treatment of corneal
neovascularization (NV). Design In a prospective, open-label, noncomparative study, 10 …

Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity

L Chen, P Hamrah, C Cursiefen, Q Zhang, B Pytowski… - Nature medicine, 2004 - nature.com
There are no studies so far linking molecular regulation of lymphangiogenesis and induction
of adaptive immunity. Here, we show that blockade of vascular endothelial growth factor …