Vitreous substitutes: a comprehensive review
TT Kleinberg, RT Tzekov, L Stein, N Ravi… - Survey of …, 2011 - Elsevier
Vitreoretinal disorders constitute a significant portion of treatable ocular disease. Advances
in vitreoretinal surgery have included the development and characterization of suitable …
in vitreoretinal surgery have included the development and characterization of suitable …
[HTML][HTML] ISCEV Standard for full-field clinical electroretinography (2015 update)
DL McCulloch, MF Marmor, MG Brigell… - Documenta …, 2015 - Springer
This document, from the International Society for Clinical Electrophysiology of Vision
(ISCEV), presents an updated and revised ISCEV Standard for full-field clinical …
(ISCEV), presents an updated and revised ISCEV Standard for full-field clinical …
Vision function abnormalities in Alzheimer disease
R Tzekov, M Mullan - Survey of Ophthalmology, 2014 - Elsevier
Alzheimer disease (AD) is a progressive, age-related debilitating condition that is a growing
public health problem in the developed world. Visual system abnormalities in AD were …
public health problem in the developed world. Visual system abnormalities in AD were …
[HTML][HTML] Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice
Rim protein (RmP) is an ABC transporter of unknown function in rod outer segment discs.
The human gene for RmP (ABCR) is affected in several recessive retinal degenerations …
The human gene for RmP (ABCR) is affected in several recessive retinal degenerations …
[HTML][HTML] The effect of human gene therapy for RPE65-associated Leber's congenital amaurosis on visual function: a systematic review and meta-analysis
X Wang, C Yu, RT Tzekov, Y Zhu, W Li - Orphanet Journal of Rare …, 2020 - Springer
Abstract Background RPE65-associated LCA (RPE65-LCA) is an inherited retinal
degeneration caused by the mutations of RPE65 gene and gene therapy has been …
degeneration caused by the mutations of RPE65 gene and gene therapy has been …
[HTML][HTML] Delayed dark-adaptation and lipofuscin accumulation in abcr+/− mice: implications for involvement of ABCR in age-related macular degeneration
NL Mata, RT Tzekov, X Liu, J Weng… - … & visual science, 2001 - arvojournals.org
purpose. To examine the ocular phenotype in mice heterozygous for a null mutation in the
abcr gene. methods. Retinas and retinal pigment epithelia (RPE) were prepared from wild …
abcr gene. methods. Retinas and retinal pigment epithelia (RPE) were prepared from wild …
[HTML][HTML] ISCEV extended protocol for the photopic negative response (PhNR) of the full-field electroretinogram
Abstract The International Society for Clinical Electrophysiology of Vision (ISCEV) Standard
for full-field electroretinography (ERG) describes a minimum procedure, but encourages …
for full-field electroretinography (ERG) describes a minimum procedure, but encourages …
Subthreshold micropulse diode laser versus conventional laser photocoagulation for diabetic macular edema: a meta-analysis of randomized controlled trials
G Chen, R Tzekov, W Li, F Jiang, S Mao, Y Tong - Retina, 2016 - journals.lww.com
Purpose: To evaluate the relative efficacy of subthreshold micropulse diode laser versus
conventional laser photocoagulation for the treatment of diabetic macular edema. Methods …
conventional laser photocoagulation for the treatment of diabetic macular edema. Methods …
Repetitive mild traumatic brain injury causes optic nerve and retinal damage in a mouse model
R Tzekov, A Quezada, M Gautier… - … of Neuropathology & …, 2014 - academic.oup.com
There is increasing evidence that long-lasting morphologic and functional consequences
can be present in the human visual system after repetitive mild traumatic brain injury (r …
can be present in the human visual system after repetitive mild traumatic brain injury (r …
Novel hydrophobically modified asymmetric RNAi compounds (sd-rxRNA) demonstrate robust efficacy in the eye
M Byrne, R Tzekov, Y Wang, A Rodgers… - Journal of ocular …, 2013 - liebertpub.com
Purpose: The major challenges of developing an RNAi therapeutic include efficient delivery
to and entry into the cell type of interest. Conventional (“naked” and chemically stabilized) …
to and entry into the cell type of interest. Conventional (“naked” and chemically stabilized) …