User profiles for "author:Robert Wojciechowski"
Robert WojciechowskiJohns Hopkins Bloomberg School of Public Health Verified email at jhu.edu Cited by 5565 |
Nature and nurture: the complex genetics of myopia and refractive error
R Wojciechowski - Clinical genetics, 2011 - Wiley Online Library
Wojciechowski R. Nature and nurture: the complex genetics of myopia and refractive error.
The refractive errors, myopia and hyperopia, are optical defects of the visual system that can …
The refractive errors, myopia and hyperopia, are optical defects of the visual system that can …
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …
[HTML][HTML] Genome-wide association studies of refractive error and myopia, lessons learned, and implications for the future
The investigation of the genetic basis of refractive error and myopia entered a new stage
with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many …
with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many …
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …
increasingly common cause of blindness. This genome-wide association meta-analysis in …
Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
JE Craig, X Han, A Qassim, M Hassall… - Nature …, 2020 - nature.com
Glaucoma, a disease characterized by progressive optic nerve degeneration, can be
prevented through timely diagnosis and treatment. We characterize optic nerve photographs …
prevented through timely diagnosis and treatment. We characterize optic nerve photographs …
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma, and
variability in IOP might herald glaucomatous development or progression. We report the …
variability in IOP might herald glaucomatous development or progression. We report the …
[PDF][PDF] Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error
Refractive errors are common eye disorders of public health importance worldwide. Ocular
axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia …
axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia …
Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia
Refractive errors, in particular myopia, are a leading cause of morbidity and disability
worldwide. Genetic investigation can improve understanding of the molecular mechanisms …
worldwide. Genetic investigation can improve understanding of the molecular mechanisms …
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
H Springelkamp, AI Iglesias, A Mishra… - Human molecular …, 2017 - academic.oup.com
Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …