Ex vivo cultured limbal epithelial stem cells have been used successfully to treat corneal
limbal stem cell deficiency. We identified 17 reports of the application of this novel cell …

Keratoconus (KC) is a common degenerative condition that frequently results in visual loss
with an onset typically in early adulthood. It is the single most common reason for …

The cornea provides the eye with protection and the refractive properties essential for visual
acuity. The transparent epithelium is highly specialized with basal and stratified squamous …

purpose. To map the collagen orientation and relative distribution of collagen fibrillar mass
in keratoconus corneal buttons. methods. Structural analysis was performed by obtaining …

Conclusions: The progression of keratoconus to a stage where penetrating keratoplasty (PK)
is required for visual rehabilitation has considerable implications for affected patients. To …

It is anticipated that stem cell (SC) therapy will enable the regeneration of diseased tissues
and organs. Understanding SC niches is an essential step toward realizing this goal. By …

PURPOSE: To compare visual function after deep anterior lamellar keratoplasty (DALK) with
visual function after penetrating keratoplasty (PK) for keratoconus and correlate this with …

The endothelium is a monolayer of cells on the posterior corneal surface that transports
water from the stroma into the anterior chamber. This movement of water counters a natural …

Purpose: To determine the clinical factors associated with the development of acute corneal
hydrops and its subsequent outcome. Methods: The authors identified 147 eyes (124 …

OBJECTIVE: To determine, using objective measures, the outcome of ex vivo cultured limbal
epithelial stem cell (LESC) transplantation performed in compliance with good …