User profiles for "author:S. Tsukahara"

Shinji Tsukahara

Saitama University, Professor
Verified email at mail.saitama-u.ac.jp
Cited by 2462

Epidemiology of glaucoma in Japan--a nationwide glaucoma survey.

Y Shiose, Y Kitazawa, S Tsukahara… - Japanese journal of …, 1991 - europepmc.org
A population-based, collaborative glaucoma survey was conducted in seven regions
throughout Japan, during the years of 1988 and 1989. The total number of subjects …

C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance

Y Imai, M Nakane, K Kage, S Tsukahara… - Molecular cancer …, 2002 - AACR
Breast cancer resistance protein (BCRP) confers multidrug resistance to cancer cells against
agents such as SN-38 (an active metabolite of irinotecan), mitoxantrone, and topotecan …

Dominant‐negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S‐S dependent homodimerization

K Kage, S Tsukahara, T Sugiyama… - … journal of cancer, 2002 - Wiley Online Library
Breast cancer resistance protein (BCRP) is a half‐molecule ABC transporter highly
expressed in mitoxantrone‐resistant cells. In our study we established PA317 transfectants …

Bursts of retrotransposition reproduced in Arabidopsis

S Tsukahara, A Kobayashi, A Kawabe, O Mathieu… - Nature, 2009 - nature.com
Retrotransposons, which proliferate by reverse transcription of RNA intermediates, comprise
a major portion of plant genomes,. Plants often change the genome size and organization …

Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance

Y Imai, S Tsukahara, S Asada, Y Sugimoto - Cancer research, 2004 - AACR
Breast cancer resistance protein (BCRP), also called ABCG2, confers resistance to
anticancer agents such as 7-ethyl-10-hydroxycamptothecin (SN-38), mitoxantrone, and …

[HTML][HTML] Sexually dimorphic formation of the preoptic area and the bed nucleus of the stria terminalis by neuroestrogens

S Tsukahara, M Morishita - Frontiers in Neuroscience, 2020 - frontiersin.org
Testicular androgens during the perinatal period play an important role in the sexual
differentiation of the brain of rodents. Testicular androgens transported into the brain act via …

Breast cancer resistance protein: molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics

Y Sugimoto, S Tsukahara, E Ishikawa… - Cancer …, 2005 - Wiley Online Library
Breast cancer resistance protein (BCRP) is a half‐molecule ATP‐binding cassette
transporter that forms a functional homodimer and pumps out various anticancer agents …

Neuronal hyperexcitability in stroke-like episodes of MELAS syndrome

T Iizuka, F Sakai, N Suzuki, T Hata, S Tsukahara… - Neurology, 2002 - AAN Enterprises
Background: The pathogenesis of stroke-like episodes in patients with mitochondrial
myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) remains …

Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells.

…, F Kashiwagi, S Tsukahara… - … & visual science, 1997 - iovs.arvojournals.org
PURPOSE: To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle
cells in vitro and to determine whether MMP release is altered by exposure to …

Breast cancer resistance protein exports sulfated estrogens but not free estrogens

Y Imai, S Asada, S Tsukahara, E Ishikawa… - Molecular …, 2003 - ASPET
Breast cancer resistance protein (BCRP), an ATP-binding cassette transporter, confers
resistance to a series of anticancer reagents such as mitoxantrone, 7-ethyl-10 …