Sepsis is a common and lethal syndrome: although outcomes have improved, mortality
remains high. No specific anti-sepsis treatments exist; as such, management of patients …

Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Cytomegalovirus (CMV) infection has historically been a major complication among
immunocompromised patients, such as solid-organ and stem-cell transplant recipients and …

Background. Early virological failure of antiretroviral therapy associated with the selection of
drug-resistant human immunodeficiency virus type 1 in treatment-naive patients is very …

Background. Few data are available regarding the immunogenicity and safety of the
pandemic influenza vaccine in immunocompromised patients. We evaluated the humoral …

Candida lusitaniae is usually susceptible to echinocandins. Beta-1, 3-glucan synthase
encoded by FKS genes is the target of echinocandins. A few missense mutations in the C …

Staphylococcus aureus small-colony variants (SCVs) are associated with unusually chronic
and persistent infections despite active antibiotic treatment. The molecular basis for this …

During severe infections, Staphylococcus aureus moves from its colonising sites to blood
and tissues and is exposed to new selective pressures, thus, potentially driving adaptive …

Deep sternal wound infection (DSWI) is a feared complication following cardiac surgery.
This study describes clinical, microbiological, and treatment outcomes of DSWI and …

Background Large-scale genomic studies of within-host diversity in Staphylococcus aureus
bacteraemia (SAB) are needed to understanding bacterial adaptation underlying …